Evidence map›Paper›PMID 41151929›Full record

ArticleJournal of clinical neurology (Seoul, Korea)2025

Association of Clopidogrel Genetic Polymorphism With Efficacy and Safety for Ischemic Stroke or Transient Ischemic Attack: A Systematic Review and Updated Meta-Analysis.

Hyungjong Park, Yo Han Jung, Sooyeoun You, Jaeseob Yun, Yun Hak Kim, Yoonkyung Chang, Moo-Seok Park, Tae-Jin Song, Kyung-Yul Lee

Abstract read
In one paragraph

Article in Journal of clinical neurology (Seoul, Korea), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Hyungjong Park *Department of Neurology, Keimyung University School of Medicine, Daegu, Korea.ORCID https://orcid.org/0000-0002-6112-2939
Yo Han Jung *Department of Neurology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-3048-4718
Sooyeoun YouDepartment of Neurology, Seoul Medical Center, Seoul, Korea.ORCID https://orcid.org/0000-0003-4753-4491
Jaeseob YunDepartment of Neurology, Keimyung University School of Medicine, Daegu, Korea.ORCID https://orcid.org/0000-0002-8884-4114
Yun Hak KimDepartment of Anatomy, School of Medicine, Pusan National University, Yangsan, Korea.ORCID https://orcid.org/0000-0002-9796-8266
Yoonkyung ChangDepartment of Neurology, Ewha Womans University Mokdong Hospital, Ewha Womans University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-0345-2278
Moo-Seok ParkDepartment of Neurology, Ewha Womans University Seoul Hospital, Ewha Womans University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-2779-095X
Tae-Jin SongDepartment of Neurology, Ewha Womans University Seoul Hospital, Ewha Womans University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-9937-762X
Kyung-Yul LeeDepartment of Neurology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-5585-7739

Funding

BK21 FOUR Program (Fostering Outstanding Universities for Research) NRF-5199990614253Institute of Information & Communications Technology Planning & Evaluation (IITP) RS-2022-II220621Korea Health Industry Development Institute RS-2023-00262087Korea Health Industry Development Institute RS-2023-00265497National Research Foundation of Korea RS-2025-16067160
6 · The paper itself

Abstract

background and purposeResearch suggests that

methodsRelevant literature was obtained from searches of PubMed, Scopus, Cochrane Central Register Controlled Trials (CENTRAL), and Embase. The outcome measures of included studies were stroke or TIA, composite vascular events as an efficacy, and bleeding as a safety outcome. This meta-analysis was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines (PROSPERO ID: CRD42024564771).

resultsAn analysis of 28 studies encompassing 11,401 patients treated with clopidogrel following stroke or TIA revealed that carriers of

conclusionsCarriers of

Indexed as

allelesclopidogrelcytochromehumansischemic stroketransient ischemic attack

Identifiers

PMID41151929
PMCPMC12569420

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.