Evidence map›Paper›PMID 41151864›Full record

ArticleCancer genomics & proteomics

Strong Association Between Higher Expression of Anillin Actin-binding Protein in Pancreatic Adenocarcinoma Tissues and Patient Survival Analyzed With the UALCAN and GEPIA Platforms Using the TCGA Database.

Shin-Nosuke Yamashita, Yoshiatsu Tanaka, Shajedul Islam, Takao Kitagawa, Kazuhiro Tokuda, Durga Paudel, Sarita Giri, Tohru Ohta, Fumiya Harada, Hiroki Nagayasu and 1 more

Abstract read
In one paragraph

Article in Cancer genomics & proteomics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Shin-Nosuke Yamashita *Advanced Research Promotion Centre, Ishikari-Tobetsu, Japan.
Yoshiatsu Tanaka *Advanced Research Promotion Centre, Ishikari-Tobetsu, Japan.
Shajedul IslamAdvanced Research Promotion Centre, Ishikari-Tobetsu, Japan.
Takao KitagawaAdvanced Research Promotion Centre, Ishikari-Tobetsu, Japan.
Kazuhiro TokudaGraduate School of Health and Welfare, Yamaguchi Prefectural University, Yamaguchi, Japan.
Durga PaudelAdvanced Research Promotion Centre, Ishikari-Tobetsu, Japan.
Sarita GiriAdvanced Research Promotion Centre, Ishikari-Tobetsu, Japan.
Tohru OhtaAdvanced Research Promotion Centre, Ishikari-Tobetsu, Japan.
Fumiya HaradaDivision of Oral and Maxillofacial Surgery School of Dentistry, Ishikari-Tobetsu, Japan.
Hiroki NagayasuDivision of Oral and Maxillofacial Surgery School of Dentistry, Ishikari-Tobetsu, Japan.
Yasuhiro KuramitsuAdvanced Research Promotion Centre, Ishikari-Tobetsu, Japan; climates@hoku-iryo-u.ac.jp.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimPancreatic adenocarcinoma (PAAD) is one of the most lethal cancers worldwide, with more than 95% of PAAD patients not surviving beyond 5 years. Due to its rapid progression, in most cases there is no time for treatment by the time the disease is diagnosed, and metastases have developed in many organs. Therefore, there is currently a need to discover prognostic markers. Anillin actin-binding protein (ANLN) is an actin-binding protein involved in cell division. Its increased expression has been reported in many types of cancer, suggesting that it may be strongly involved in the progression of cancer malignancy, such as invasion and metastasis. The purpose of this study was to use bioinformatics to examine the possibility that ANLN may be a useful prognostic marker for PAAD. MATERIALS AND

methodsThe Gene Expression Profiling Interactive Analysis (GEPIA) and the University of ALabama at Birmingham CANcer data analysis Portal (UALCAN) bioinformatics platforms were used to analyze

results

conclusionIncreased expression of

Indexed as

AdenocarcinomaBiomarkers, TumorMicrofilament ProteinsPancreatic NeoplasmsComputational BiologyDatabases, GeneticFemaleGene Expression ProfilingGene Expression Regulation, NeoplasticHumansMaleMiddle AgedPrognosisANLN protein, humanBiomarkers, TumorMicrofilament ProteinsANLNGEPIApancreatic adenocarcinomaTCGAUALCAN

Identifiers

PMID41151864
PMCPMC12577607

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.