Evidence map›Paper›PMID 41151863›Full record

ArticleCancer genomics & proteomics

Oxysterol-binding Protein-like 3 Promotes Tumor Progression by Regulating Apoptosis and Angiogenesis in Colorectal Cancer.

Chan-Muk Im, Hyung-Hoon Oh, Sun-Young Park, Young-Lan Park, Jae-Sung Kim, Young-Eun Joo

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancer genomics & proteomics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chan-Muk ImDepartment of Internal Medicine, Chonnam National University Medical School, Gwangju, Republic of Korea.
Hyung-Hoon OhDepartment of Internal Medicine, Chonnam National University Medical School, Gwangju, Republic of Korea.
Sun-Young ParkDepartment of Internal Medicine, Chonnam National University Medical School, Gwangju, Republic of Korea.
Young-Lan ParkDepartment of Internal Medicine, Chonnam National University Medical School, Gwangju, Republic of Korea; yejoo@chonnam.ac.kr.
Jae-Sung KimDepartment of Oral Physiology, School of Dentistry, Chosun University, Gwangju, Republic of Korea.
Young-Eun JooDepartment of Internal Medicine, Chonnam National University Medical School, Gwangju, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimOxysterol-binding protein-like 3 (OSBPL3) is a member of the intracellular lipid receptor and transporter protein family involved in regulating lipid metabolism. Altered OSBPL3 expression has been observed in various cancers, where it has been associated with both oncogenic and tumor-suppressive roles. However, its precise functions and underlying mechanisms in colorectal cancer (CRC) remain unclear. This study aimed to investigate the role of OSBPL3 in CRC cells and evaluate its prognostic significance. MATERIALS AND

methodsA small interfering RNA vector targeting

results

conclusionOSBPL3 contributes to CRC progression by regulating tumor cell apoptosis and angiogenesis.

Indexed as

ApoptosisColorectal NeoplasmsNeovascularization, PathologicReceptors, SteroidAgedAngiogenesisCell Line, TumorCell MovementCell ProliferationDisease ProgressionFemaleGene Expression Regulation, NeoplasticHumansMaleMiddle AgedOxysterol Binding ProteinsOxysterol Binding ProteinsReceptors, Steroidangiogenesisapoptosiscolorectal neoplasmOxysterol-binding protein-like 3prognosis

Identifiers

PMID41151863
PMCPMC12577601

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.