Evidence map›Paper›PMID 41151759›Full record

ArticleJournal of biophotonics2026

Direct Detection of Viruses Using Antibody-Modified Gold Nanorods.

Axell Rodriguez, Yana Purvinsh, Aidan P Holman, Dmitry Kurouski

Abstract read
In one paragraph

Article in Journal of biophotonics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Axell RodriguezDepartment of Biochemistry and Biophysics, Texas A&M University, College Station, Texas, USA.ORCID 0009-0006-0640-9714
Yana PurvinshDepartment of Biochemistry and Biophysics, Texas A&M University, College Station, Texas, USA.
Aidan P HolmanDepartment of Biochemistry and Biophysics, Texas A&M University, College Station, Texas, USA.ORCID 0000-0003-4244-7348
Dmitry KurouskiDepartment of Biochemistry and Biophysics, Texas A&M University, College Station, Texas, USA.ORCID 0000-0002-6040-4213

Funding

Regulatory Science in Environmental Health and ToxicologyT32ES026568 · NIEHS · TEXAS A&M UNIVERSITY · PI Weihsueh A Chiu, Natalie M Johnson · 2016 to 2026
$3.8M
Biophysical determination of the underlying cause of α-Syn oligomer toxicityR35GM142869 · NIGMS · TEXAS A&M AGRILIFE RESEARCH · PI KUROUSKI, DMITRY · 2021 to 2025
$1.6M
Cross-Border Threat Screening and Supply Chain DefenseNIEHS NIH HHS T32 ES026568NIGMS NIH HHS R35 GM142869
6 · The paper itself

Abstract

Seasonal and sporadic viral infections put enormous burdens on global health and society. Although polymerase chain reaction (PCR) and other molecular approaches can be used to detect and identify viruses, they require substantial sample processing time and often have limited portability, limiting their utility in point-of-care settings. In the current study, we investigate the accuracy of direct sensing of two bacteriophages using chemically modified gold nanorods (AuNRs). We demonstrate that when using functionalized polyethylene glycol (PEG), the surface of AuNRs can be modified with desired antibodies against a particular pathogen. Furthermore, PEG protects and passivates the surface of AuNRs against unspecific binding of biomolecules that can be present in the body fluids. We also showed that dynamic light scattering (DLS) was capable of detecting virus-bound AuNRs, enabling confirmatory detection of viruses. These results indicate that antibody-modified AuNRs can be used for the confirmatory detection of various viruses.

Indexed as

AntibodiesGoldNanotubesVirusesPolyethylene GlycolsAntibodiesGoldPolyethylene Glycolsdynamic light scatteringgold nanorodsmachine learningviruses

Identifiers

PMID41151759
PMCPMC12861120

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.