ReviewNeuron2025
Between planning and map building: Prioritizing replay when future goals are uncertain.
Review in Neuron, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed.
- The hippocampus as a generative model.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2026Review
- Planning in the Brain: It's Not What You Think It Is.Annual review of neuroscience · 2026Review
- Flexible route planning and rapid structure learning by mice in complex environments.bioRxiv : the preprint server for biology · 2026Article
- Article
- Article
- Trial-by-trial learning of successor representations in human behavior.PLoS computational biology · 2025Article
- Proactive and reactive construction of memory-based preferences.bioRxiv : the preprint server for biology · 2024Article
Corrections and comments
- Update of
Authors and funding
4 authors.
Funding
Abstract
Despite many empirical results about hippocampal replay, its computational function remains controversial. The "value" hypothesis contends that replay plans routes to current goals, while the "map" hypothesis holds that replay builds an abstract environmental representation, distinct from immediate goals. Data appear to support either view, though the planning hypothesis is particularly challenged by recent observations of replay lagging, rather than leading, animals learning to reach current goals. However, differentiating these ideas is difficult due to a lack of formal specificity, especially about the map hypothesis. We address these gaps by extending a prominent theory of planning to include routes to future as well as current goals: effectively a map. Whether replay prefers current goals, like planning, or others, like maps, then depends on their estimated likelihood of future relevance. This account reconciles both views with one another and with much data, revealing a deep relationship between the seemingly distinct hypotheses.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.