Evidence map›Paper›PMID 41151063›Full record

Trial reportThe Journal of urology2026

Impact of Renal Mass Biopsy on Decision-Making Experience for Clinical T1 Renal Masses.

Kathryn H Gessner, Allison M Deal, Amir Feinberg, Shannon Myers, Katherine Poulos, Hillary Heiling, Sara Wobker, Pranav Akella, Marc A Bjurlin, Clayton Commander and 8 more

Abstract readComparative StudyClinical Trial
In one paragraph

Trial report in The Journal of urology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

18 authors.

Kathryn H GessnerDepartment of Urology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.ORCID 0000-0002-0335-4467
Allison M DealLineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Amir FeinbergDepartment of Urology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Shannon MyersDepartment of Urology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Katherine PoulosSchool of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Hillary HeilingDepartment of Biostatistics, Dana Farber Cancer Institute, Boston, Massachusetts.
Sara WobkerDepartment of Urology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Pranav AkellaDepartment of Urology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Marc A BjurlinDepartment of Urology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Clayton CommanderDepartment of Interventional Radiology, MBB Radiology, Jacksonville, Florida.
Matthew I MilowskyLineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Matthew E NielsenDepartment of Urology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Mathew RaynorDepartment of Urology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Angela B SmithDepartment of Urology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Eric WallenDepartment of Urology, Medical University of South Carolina, Charleston, South Carolina.
David C JohnsonDepartment of Urology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
William Y KimLineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Hung-Jui TanDepartment of Urology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.

Funding

Re-Entry Supplement: Investigation of Oral Microbial Enzymes for the Detection and Treatment of Periodontal DiseaseUL1TR002489 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BUSE, JOHN BERNARD, SHAHEEN, NICHOLAS J · 2018 to 2022
$48.6M
North Carolina Translational and Clinical Sciences Institute (NC TraCS)UM1TR004406 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI NICHOLAS J SHAHEEN · 2023 to 2026
$37.5M
UNC Oncology K12K12CA120780 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI WILLIAM Y. KIM · 2007 to 2026
$9.6M
UNC Integrated Translational Oncology Program (UNC-iTOP)T32CA244125 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI WILLIAM Y. KIM, Jen Jen Yeh · 2019 to 2026
$3.9M
NCATS NIH HHS UL1 TR002489NCATS NIH HHS UM1 TR004406NCI NIH HHS K12 CA120780NCI NIH HHS T32 CA244125
6 · The paper itself

Abstract

purposeOwing to uncertainty on best management, a subset of patients with small renal masses suspicious for kidney cancer experience elevated decisional conflict. We hypothesize that pathologic information from renal mass biopsy (RMB) may improve patient decision-making. In this study, we evaluate the impact of RMB on decisional conflict for patients with clinical T1 renal masses. MATERIALS AND

methodsA comparative, nonrandomized clinical trial was performed at a large tertiary cancer center. Patients with new clinical T1 renal masses were self-assigned to standard-of-care biopsy. We used difference-in-difference (DiD) analyses to assess change in decisional conflict scale by receipt of RMB.

resultsAmong 250 participants, 25% underwent biopsy during the initial decision-making period before definitive intervention. Biopsy was more common for patients with masses > 4 cm vs 0 to 2 cm (prevalence ratios [PR] 2.41, 95% CI: 1.20-4.82,

conclusionsThough RMB did not significantly decrease decisional conflict in all patients, biopsy reduced decisional conflict in certain patient subsets, demonstrating the importance of further investigating how to better support patients after renal mass diagnosis.

Indexed as

Clinical Decision-MakingDecision MakingKidneyKidney NeoplasmsAgedBiopsyFemaleHumansMaleMiddle AgedNeoplasm Stagingcore needle biopsyrenal cell carcinomashared decision-making

Identifiers

PMID41151063
PMCPMC12704500

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.