ReviewCurrent issues in molecular biology2025
Research Progress on the Relationship Between the Intestinal Barrier and Macrophages.
Review in Current issues in molecular biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Macrophage-driven inflammation in inflammatory bowel disease: mechanisms and therapeutic opportunities.Frontiers in bioengineering and biotechnology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
The intestinal barrier serves as a crucial defense in the body, and a compromised integrity can lead to systemic health issues. Intestinal macrophages, as key components of the intestinal immune system, have a profound influence on intestinal homeostasis. However, the complex mechanisms underlying interactions between the intestinal barrier and intestinal macrophages remain incompletely elucidated. This review systematically summarizes the bidirectional regulatory relationship between them. It specifically focuses on how the intestinal barrier impacts the phenotype, function, and heterogeneity of macrophages while concurrently analyzing the pivotal role of macrophages in maintaining and repairing intestinal barrier function. Furthermore, this review provides an in-depth analysis of the critical influence of this interaction on the pathogenesis and progression of various intestinal disorders and systemic diseases. By synthesizing and summarizing current research advances, this review aims to enhance the understanding of the regulatory mechanisms underlying intestinal immune homeostasis and to lay a theoretical foundation for developing novel strategies for the prevention and treatment of related diseases.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.