Evidence map›Paper›PMID 41150612›Full record

ArticleBrazilian journal of cardiovascular surgery2025

Influence of Frailty Syndrome on Outcomes of Cardiovascular Surgery in Elderly Patients.

Felipe Borsu de Salles, Gabriella Zanin Fighera, Veridiana Borges Costa, Kalil Hussein Khalil, Renato Abdala Karam Kalil, Bruna Eibel

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Article in Brazilian journal of cardiovascular surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Felipe Borsu de SallesInstituto de Cardiologia Porto Alegre Rio Grande do Sul Brazil Instituto de Cardiologia, Porto Alegre, Rio Grande do Sul, Brazil.
Gabriella Zanin FigheraInstituto de Cardiologia Porto Alegre Rio Grande do Sul Brazil Instituto de Cardiologia, Porto Alegre, Rio Grande do Sul, Brazil.
Veridiana Borges CostaInstituto de Cardiologia Porto Alegre Rio Grande do Sul Brazil Instituto de Cardiologia, Porto Alegre, Rio Grande do Sul, Brazil.
Kalil Hussein KhalilUniversidade de São Paulo Faculdade de Medicina Instituto do Coração do Hospital das Clínicas São Paulo São Paulo Brazil Instituto do Coração do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, São Paulo, Brazil.
Renato Abdala Karam KalilFundação Universitária de Cardiologia Instituto de Cardiologia do Rio Grande do Sul Porto Alegre Rio Grande do Sul Brazil Instituto de Cardiologia do Rio Grande do Sul - Fundação Universitária de Cardiologia, Porto Alegre, Rio Grande do Sul, Brazil.
Bruna EibelInstituto de Cardiologia Porto Alegre Rio Grande do Sul Brazil Instituto de Cardiologia, Porto Alegre, Rio Grande do Sul, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionFrailty syndrome is a significant risk factor for elderly patients undergoing cardiovascular surgery. However, there is no consensus on which criteria are most effective for assessing frailty in this context.

objectiveThis study aimed to evaluate the relationship between different widely cited frailty syndrome criteria and postoperative morbidity and mortality.

methodsPatients aged ≥ 60 years scheduled for coronary artery bypass graft, valve, and/or ascending aortic surgery were assessed for frailty preoperatively. Frailty was defined by Clinical Frailty Scale (CFS) ≥ 4, Katz Index ≥ 1, Short Physical Performance Battery (SPPB) ≤ 6, Fried Frailty Phenotype (FFP) ≥ 3 or abnormal values in 15-feet gait speed (GS) test, or hand grip strength. Clinical outcomes, including mortality and major adverse cardiovascular and cerebral events (MACCE), were assessed 30 days post-surgery.

resultsAmong 137 patients (70.1% male, mean age 69.43 ± 5.98 years), frailty prevalence ranged from 13.1% to 43.1%, depending on criterion, with no significant differences by age strata or surgery type. At 30-day follow-up, mortality was 5.1% (n = 7), and a total of 29 MACCE (21.1%) were recorded. Patients identified as frail by the FFP, CFS, SPPB, and GS criteria showed a significant association with mortality and MACCE. Multivariate analysis indicated FFP and CFS as independent risk factors for MACCE with equivalent prognostic prediction.

conclusionFrailty is a prevalent condition among elderly patients undergoing cardiovascular surgery and is associated with mortality and morbidity. Frailty defined by FFP and CFS criteria was independently associated with higher MACCE rates.

Indexed as

Cardiovascular Surgical ProceduresFrail ElderlyFrailtyPostoperative ComplicationsAgedAged, 80 and overFemaleGeriatric AssessmentHand StrengthHumansMaleMiddle AgedRisk AssessmentRisk FactorsTreatment OutcomeCardiac SurgeryFrailtyMajor Adverse Cardiovascular Cerebral Events.Mortality

Identifiers

PMID41150612
PMCPMC12581427

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