Evidence map›Paper›PMID 41150496›Full record

ArticleSports (Basel, Switzerland)2025

Feasibility and Preliminary Effects of Community-Based High-Intensity Functional Training for Adults with Mobility Disabilities and Overweight/Obesity: A Pilot Study.

Lyndsie M Koon, Joseph E Donnelly, Joseph R Sherman, Anna M Rice, Julianne G Clina, John Thyfault, Reed Handlery, Kaci Handlery, Derek A Crawford

Abstract read
In one paragraph

Article in Sports (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Lyndsie M KoonResearch and Training Center on Independent Living (KU-RTCIL), Life Span Institute, University of Kansas, 1000 Sunnyside Ave., Room 4089, Lawrence, KS 66045, USA.ORCID 0000-0002-4362-1398
Joseph E DonnellyPhysical Activity and Weight Management Division (DPAWM), University of Kansas Medical Center Internal Medicine, 3901 Rainbow Boulevard Mailstop 1007, Kansas City, KS 66160, USA.
Joseph R ShermanPhysical Activity and Weight Management Division (DPAWM), University of Kansas Medical Center Internal Medicine, 3901 Rainbow Boulevard Mailstop 1007, Kansas City, KS 66160, USA.
Anna M RicePhysical Activity and Weight Management Division (DPAWM), University of Kansas Medical Center Internal Medicine, 3901 Rainbow Boulevard Mailstop 1007, Kansas City, KS 66160, USA.ORCID 0009-0005-4973-7390
Julianne G ClinaPhysical Activity and Weight Management Division (DPAWM), University of Kansas Medical Center Internal Medicine, 3901 Rainbow Boulevard Mailstop 1007, Kansas City, KS 66160, USA.ORCID 0000-0002-3655-5644
John ThyfaultDepartments of Cell Biology and Physiology, Internal Medicine-Endocrinology, Kansas Center for Metabolism and Obesity Research, University of Kansas Diabetes Institute, Kansas City, KS 66160, USA.
Reed HandlerySchool of Physical Therapy, Arkansas Colleges of Health Education, Fort Smith, AR 72916, USA.ORCID 0000-0003-0064-6808
Kaci HandlerySchool of Physical Therapy, Arkansas Colleges of Health Education, Fort Smith, AR 72916, USA.ORCID 0000-0002-7362-5939
Derek A CrawfordDepartment of Nutrition, Kinesiology & Health, University of Central Missouri, Warrensburg, MO 64093, USA.

Funding

University of Kansas Alzheimer's Disease Research Center (KU ADRC)P30AG072973 · NIA · UNIVERSITY OF KANSAS MEDICAL CENTER · PI Mohammad Haeri · 2021 to 2026
$25.3M
longitudinal assessment of stress and stress-related concepts across a behavioral weight loss interventionP20GM144269 · NIGMS · UNIVERSITY OF KANSAS MEDICAL CENTER · PI John P Thyfault, STEVEN A WEINMAN · 2022 to 2026
$14.9M
Multidisciplinary Research Training Program in Alzheimer's Disease and Related DisordersT32AG078114 · NIA · UNIVERSITY OF KANSAS MEDICAL CENTER · PI Sandra A Billinger, Eric Dennis Vidoni · 2022 to 2026
$1.2M
NIA NIH HHS P30 AG072973NIA NIH HHS T32 AG078114NIGMS NIH HHS P20 GM144269NIGMS NIH HHS P20GM144269
6 · The paper itself

Abstract

backgroundPreliminary evidence supports high-intensity functional training (HIFT) for improving various health outcomes in non-disabled adults with overweight/obesity. It remains unknown whether HIFT produces similar benefits in individuals who are overweight/obese and also have a mobility disability (e.g., spinal cord injury, multiple sclerosis)-a population disproportionately affected by obesity-related health conditions and systemic barriers to exercise. This pilot study aimed to evaluate the feasibility and preliminary effects of a 24-week HIFT intervention, delivered at community sites by certified trainers, for adults with mobility disabilities (MDs) who were overweight/obese.

methodsTwenty adults with MD and overweight/obesity (self-reported BMI 25-46 kg/m

resultsFeasibility targets were met, with a recruitment rate of 72.2%, 76.9% retention, and 80.7% attendance. Thirteen adverse events occurred. Effects on obesity-related measures ranged from negligible to moderate, with stable weight/BMI, reduced waist circumference (45% ≥ 3 cm decrease), decreased body fat, and increased lean mass. Functional outcome effects ranged from small to large and included grip strength, balance, and walking speed. Large improvements were observed for the endurance, speed, work capacity, and self-reported physical function.

conclusionsA community-based HIFT program is feasible and may improve health outcomes in adults with MD and overweight/obesity.

Indexed as

adaptive exercisecommunity-based exercisefeasibilityhigh-intensity functional trainingmobility disabilityobesityphysical functionpilot study

Identifiers

PMID41150496
PMCPMC12567876

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.