Evidence map›Paper›PMID 41150461›Full record

ArticleVaccines2025

Improving the Suitability of Vaccine Design for Immunisation Programmes and Enhancing Vaccine Policy Quality Through User Research.

Stefano Malvolti, Melissa Malhame, Adam Soble, Carsten Mantel, Melissa Ko, Lorena Perrin, Tiziana Scarna, Marion Menozzi-Arnaud, Jean-Pierre Amorij

Abstract read
In one paragraph

Article in Vaccines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Stefano MalvoltiMMGH Consulting GmbH, 8049 Zurich, Switzerland.ORCID 0000-0003-0146-1127
Melissa MalhameMMGH Consulting GmbH, 8049 Zurich, Switzerland.ORCID 0009-0001-6753-6518
Adam SobleMMGH Consulting GmbH, 8049 Zurich, Switzerland.
Carsten MantelMMGH Consulting GmbH, 8049 Zurich, Switzerland.ORCID 0009-0005-1527-3065
Melissa KoMMGH Consulting GmbH, 8049 Zurich, Switzerland.
Lorena PerrinImpact Hub, 8005 Zurich, Switzerland.
Tiziana ScarnaGavi, The Vaccine Alliance, 1218 Geneva, Switzerland.
Marion Menozzi-ArnaudGavi, The Vaccine Alliance, 1218 Geneva, Switzerland.
Jean-Pierre AmorijUNICEF Supply Division, 2150 Copenhagen, Denmark.

Funding

Wellcome Trust
6 · The paper itself

Abstract

backgroundThe achievement of the goals of the Immunization Agenda 2030 (IA2030) requires vaccines to be developed and implemented that meet the needs and requirements of the final users: vaccinators and vaccinees. A detailed and shared understanding of these needs should inform policy and programme guidance directing stakeholders' efforts and investments. Currently, relevant guidance documents only partially capture vaccine users' perspectives.

methodTo help overcome this gap, we propose an operational research method grounded in the principles of the design approach that systematically maps and integrates user perspectives in vaccine development, policy, and implementation decisions.

resultsThe method, named the seven Ws, guides researchers through a three-step process. First, it clarifies the contribution of a vaccine to solving a public health problem-the solution-problem fit. Second, it maps potential implementation strategies for the vaccine in different settings. Lastly, it describes the relevant vaccine's use cases across the implementation strategies, elucidating the user requirements for the vaccine to be successfully implemented-the solution-provider and solution-user fits.

conclusionsBy explicitly pursuing these three fits, policymakers, vaccine developers, and programme managers will be able to better contribute towards the achievement of the IA2030 goals. This framework is intended as a conceptual contribution rather than an empirical validation study.

Indexed as

design approachIA2030implementation strategyproduct developmentuse casesuser researchvaccines

Identifiers

PMID41150461
PMCPMC12567887

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.