Evidence map›Paper›PMID 41150429›Full record

ArticleVaccines2025

Production of Clinical-Grade SARS-CoV-2 Spike Ferritin Nanoparticle Protein Immunogen by Transient Transfection.

Agnes Hajduczki, William C Chang, Rafael De La Barrera, James F Wood, Wei-Hung Chen, Elizabeth J Martinez, Jaime L Jensen, Rajeshwer S Sankhala, Clayton Smith, Alexander Anderson and 26 more

Abstract read
In one paragraph

Article in Vaccines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

36 authors.

Agnes HajduczkiViral Diseases Program, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA.
William C ChangViral Diseases Program, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA.ORCID 0000-0003-4967-6426
Rafael De La BarreraPilot Bioproduction Facility, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA.
James F WoodPilot Bioproduction Facility, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA.
Wei-Hung ChenViral Diseases Program, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA.
Elizabeth J MartinezViral Diseases Program, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA.ORCID 0000-0002-7755-7056
Jaime L JensenViral Diseases Program, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA.ORCID 0000-0002-8818-7513
Rajeshwer S SankhalaViral Diseases Program, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA.
Clayton SmithCenter for Molecular Microscopy, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD 21702, USA.
Alexander AndersonHenry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD 20817, USA.ORCID 0000-0002-0000-7734
Elaine B MorrisonU.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA.
Caroline E PetersonViral Diseases Program, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA.ORCID 0000-0002-6087-7301
Phyllis A ReesViral Diseases Program, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA.
Sandrine SomanViral Diseases Program, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA.
Caitlin KuklisViral Diseases Program, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA.
Aslaa AhmedViral Diseases Program, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA.
Jocelyn KingViral Diseases Program, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA.
Farooq NasarViral Diseases Program, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA.
Courtney CorbittViral Diseases Program, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA.
Misook ChoeViral Diseases Program, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA.
Paul V ThomasViral Diseases Program, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA.ORCID 0000-0002-6772-3997
Michelle ZemilU.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA.
Lindsay WieczorekHenry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD 20817, USA.
Victoria R PolonisU.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA.
Helen M DooleyInstitute of Marine and Environmental Technology, University of Maryland School of Medicine, Baltimore, MD 21202, USA.ORCID 0000-0002-2570-574X
John R MascolaVaccine Research Center, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD 20852, USA.
Natalie de ValCenter for Molecular Microscopy, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD 21702, USA.
Gary R MatyasU.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA.ORCID 0000-0002-2074-2373
Mangala RaoU.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA.
Gregory D GromowskiViral Diseases Program, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA.ORCID 0000-0003-4576-4277
Kayvon ModjarradViral Diseases Program, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA.
Sandhya VasanHenry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD 20817, USA.
Jeffrey W FroudePilot Bioproduction Facility, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA.
Nelson L MichaelCenter for Infectious Diseases Research, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA.
M Gordon JoyceViral Diseases Program, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA.ORCID 0000-0002-6808-7232
Stasya ZarlingPilot Bioproduction Facility, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA.

Funding

United States Department of Defense W81XWH-18-2-0040
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

adjuvanted vaccineALFQ adjuvantCGMP productionCOVID-19pandemic preparednessrecombinant protein vaccineSARS-CoV-2structure-based vaccine designtransient transfection

Identifiers

PMID41150429
PMCPMC12567911

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.