Evidence map›Paper›PMID 41150400›Full record

ArticleVaccines2025

Polyphosphazene-Mediated Assembly of TLR4 and TLR7/8 Agonists Enables a Potent Nano-Adjuvant Delivery System for Hepatitis C Virus Vaccine Antigens.

Alexander K Andrianov, Alexander Marin, Sarah Jeong, Liudmila Kulakova, Ananda Chowdhury, Raman Hlushko, Sayan Das, Francesca Moy, Eric A Toth, Robert K Ernst and 1 more

Abstract read
In one paragraph

Article in Vaccines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Alexander K AndrianovInstitute for Bioscience and Biotechnology Research, University of Maryland, Rockville, MD 20850, USA.ORCID 0000-0001-6186-6156
Alexander MarinInstitute for Bioscience and Biotechnology Research, University of Maryland, Rockville, MD 20850, USA.
Sarah JeongInstitute for Bioscience and Biotechnology Research, University of Maryland, Rockville, MD 20850, USA.
Liudmila KulakovaInstitute for Bioscience and Biotechnology Research, University of Maryland, Rockville, MD 20850, USA.
Ananda ChowdhuryInstitute for Bioscience and Biotechnology Research, University of Maryland, Rockville, MD 20850, USA.
Raman HlushkoInstitute for Bioscience and Biotechnology Research, University of Maryland, Rockville, MD 20850, USA.ORCID 0000-0003-3969-5404
Sayan DasDepartment of Microbial Pathogenesis, School of Dentistry, University of Maryland, Baltimore, MD 21021, USA.
Francesca MoyDepartment of Microbial Pathogenesis, School of Dentistry, University of Maryland, Baltimore, MD 21021, USA.
Eric A TothInstitute for Bioscience and Biotechnology Research, University of Maryland, Rockville, MD 20850, USA.ORCID 0000-0002-0766-5131
Robert K ErnstDepartment of Microbial Pathogenesis, School of Dentistry, University of Maryland, Baltimore, MD 21021, USA.ORCID 0000-0001-5016-8694
Thomas R FuerstInstitute for Bioscience and Biotechnology Research, University of Maryland, Rockville, MD 20850, USA.ORCID 0000-0002-9766-9995

Funding

Rational design and efficacy testing of vaccines against HCVR01AI168048 · NIAID · UNIV OF MARYLAND, COLLEGE PARK · PI Alexander Andrianov, Thomas R Fuerst · 2022 to 2026
$7.1M
NIAID NIH HHS R01 AI168048NIH HHS HHS-NIH-NIAID-BAA2017NIH HHS R01 AI132212NIH HHS R01 AI168048
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Hepatitis C virusintermolecular interactionspolyphosphazenesToll-like receptor agonistvaccine adjuvantsvaccine delivery

Identifiers

PMID41150400
PMCPMC12567633

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.