ArticleTropical medicine and infectious disease2025
Prognostic Significance of CRP/Albumin, D-Dimer/Albumin, D-Dimer/Fibrinogen Ratios and Triglyceride-Glucose Index in Crimean-Congo Hemorrhagic Fever: A Prospective Observational Study.
Article in Tropical medicine and infectious disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundCrimean-Congo hemorrhagic fever (CCHF) is a severe zoonotic viral infection with high mortality rates. This study aimed to examine the prognostic value of new-generation inflammatory markers-CRP/albumin ratio (CAR), D-dimer/albumin ratio (DAR), D-dimer/fibrinogen ratio (DFR), and triglyceride-glucose index (TGI)-in predicting mortality among patients diagnosed with CCHF.
methodsThis prospective study involved 76 patients with a positive polymerase chain reaction test for CCHF and 38 age- and sex-matched healthy controls between 15 April 2023 and 15 October 2024. Participants' demographic, clinical, and laboratory data at presentation were recorded.
resultsCAR, DAR, DFR, and TGI levels were significantly higher in the patient group compared to the control group (all
conclusionsInflammatory markers CAR, DAR, DFR and TGI may serve as significant prognostic tools to predict mortality in CCHF.
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