Evidence map›Paper›PMID 41150363›Full record

ReviewTropical medicine and infectious disease2025

Gender-Associated Factors on the Occurrence and Prevalence of Zero-Dose Children in Sub-Saharan Africa: A Critical Literature Review.

Godfrey Musuka, Enos Moyo, Patrick Gad Iradukunda, Pierre Gashema, Roda Madziva, Helena Herrera, Tapiwa Dhliwayo, Constantine Mutata, Noah Mataruse, Oscar Mano and 2 more

Abstract readReview
In one paragraph

Review in Tropical medicine and infectious disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Godfrey MusukaInternational Initiative for Impact Evaluation, Harare P.O. Box 0002, Zimbabwe.ORCID 0000-0001-9077-4429
Enos MoyoDepartment of Public Health Medicine, University of KwaZulu-Natal, Durban 4041, South Africa.ORCID 0000-0002-1827-9551
Patrick Gad IradukundaPolicy Research Centre, Department of Research, Kigali 00000, Rwanda.ORCID 0000-0002-0236-7776
Pierre GashemaPolicy Research Centre, Department of Research, Kigali 00000, Rwanda.
Roda MadzivaSchool of Sociology and Social Policy, University of Nottingham, Nottingham NG7 2RD, UK.
Helena HerreraSchool of Medicine, Pharmacy and Biomedical Sciences, University of Portsmouth, Portsmouth PO1 2UP, UK.ORCID 0000-0003-0107-8128
Tapiwa DhliwayoDepartment of Community Medicine, Midlands State University, Gweru P.O. Box 9055, Zimbabwe.
Constantine MutataDepartment of Community Medicine, Midlands State University, Gweru P.O. Box 9055, Zimbabwe.
Noah MataruseUNICEF, 2150 Copenhagen, Denmark.ORCID 0000-0001-8441-163X
Oscar ManoDepartment of Public Health, University of the Western Cape, Robert Sobukwe Road, Bellville 7535, South Africa.ORCID 0009-0001-9670-4939
Elliot MbungeDepartment of Applied Information Systems, University of Johannesburg, Johannesburg 2092, South Africa.ORCID 0000-0003-4504-6697
Tafadzwa DzinamariraSchool of Health Systems and Public Health, University of Pretoria, Pretoria 0002, South Africa.ORCID 0000-0002-9929-5739

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundImmunisation remains one of the most effective and cost-efficient public health interventions for preventing infectious diseases in children. Despite global progress, Sub-Saharan Africa (SSA) continues to face challenges in achieving equitable immunisation coverage. Gender-related disparities, rooted in sociocultural and structural inequalities, significantly influence the prevalence of zero-dose and under-immunised children in the region. This review critically examines the gender-associated barriers to routine childhood immunisation in SSA to inform more inclusive and equitable health interventions.

methodsA critical literature review was conducted generally following some steps of the PRISMA-P and CRD guidelines. Using the Population-Concept-Context (PCC) framework, studies were selected that examined gender-related barriers to routine immunisation for children under five in Sub-Saharan Africa. Comprehensive searches were performed across PubMed, Google Scholar, and relevant organisational websites, targeting articles published between 2015 and 2025. A total of 3683 articles were retrieved, with 24 studies ultimately meeting the inclusion criteria. Thematic analysis was used to synthesise the findings.

resultsFour major themes emerged: (1) women's empowerment and autonomy, including limited decision-making power, financial control, and the impact of gender-based violence; (2) male involvement and prevailing gender norms, where patriarchal structures and low male engagement negatively influenced vaccine uptake; (3) socioeconomic and structural barriers, such as poverty, geographic inaccessibility, maternal workload, and service availability; and (4) education, awareness, and health system responsiveness.

conclusionsGender dynamics have a significant impact on childhood immunisation outcomes in Sub-Saharan Africa. Future policies must integrate these insights to improve immunisation equity and reduce preventable child morbidity and mortality across the region.

Indexed as

genderimmunisationsub-Saharan Africazero dosezero-dose

Identifiers

PMID41150363
PMCPMC12568239

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.