The Construction and Characterization of an Infectious Clone of the Asian Genotype Chikungunya Virus from Yunnan, China.

Xinhang Ning, Binghui Xia, Zimeng Cheng, Liuyi Zhang, Fengfeng Mo, Hao Ren, Hailin Tang

Abstract read

In one paragraph

Article in Tropical medicine and infectious disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xinhang NingDepartment of Biomedical Protection, Faculty of Naval Medicine, Naval Medical University, Shanghai 200433, China.

Binghui XiaDepartment of Biomedical Protection, Faculty of Naval Medicine, Naval Medical University, Shanghai 200433, China.

Zimeng ChengDepartment of Biomedical Protection, Faculty of Naval Medicine, Naval Medical University, Shanghai 200433, China.ORCID 0009-0001-5401-9319

Liuyi ZhangDepartment of Biomedical Protection, Faculty of Naval Medicine, Naval Medical University, Shanghai 200433, China.

Fengfeng MoDepartment of Naval Nutrition and Food Hygiene, Faculty of Naval Medicine, Naval Medical University, 800 Xiangyin Road, Shanghai 200433, China.

Hao RenDepartment of Biomedical Protection, Faculty of Naval Medicine, Naval Medical University, Shanghai 200433, China.

Hailin TangDepartment of Biomedical Protection, Faculty of Naval Medicine, Naval Medical University, Shanghai 200433, China.ORCID 0000-0002-4090-8852

Funding

National Key R&D Program of China 2022YFC2602901, 2022YFC2602903

6 · The paper itself

Abstract

Chikungunya fever (CHIKF), which is caused by the Chikungunya virus (CHIKV), has rapidly spread across the globe in recent years, leading to its listing as a public health concern by the World Health Organization. In 2019, the first local outbreak of Asian-type CHIKF was reported in Xishuangbanna, Yunnan Province, China, with 88 CHIKV nucleic acid-positive cases detected from clinical specimens. To further investigate the biological characteristics of the virus strain responsible for this outbreak, we reconstructed the 625D6h strain using reverse genetics and tested its growth kinetics in different cell lines. The results showed a strong replication capacity in the

Indexed as

Asian genotypeChikungunya virusinfectious clonereverse genetics

Identifiers

PMID41150355

DOI10.3390/tropicalmed10100278

PMCPMC12567886

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