Evidence map›Paper›PMID 41150293›Full record

ArticlePolymers2025

Immune Protective Effect of Chitosan Oligosaccharide on Lipopolysaccharide-Stimulated Coelomocytes of Sea Cucumber

Rongyue Wang, Xiaoyu Nie, Xiaofan Li, Jinwei Tang, Chong Huang, Juan Liu

Abstract read
In one paragraph

Article in Polymers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rongyue WangCollege of Fisheries and Life Science, Dalian Ocean University, Dalian 116023, China.
Xiaoyu NieCollege of Fisheries and Life Science, Dalian Ocean University, Dalian 116023, China.
Xiaofan LiCollege of Fisheries and Life Science, Dalian Ocean University, Dalian 116023, China.
Jinwei TangCollege of Fisheries and Life Science, Dalian Ocean University, Dalian 116023, China.
Chong HuangCollege of Fisheries and Life Science, Dalian Ocean University, Dalian 116023, China.
Juan LiuCollege of Fisheries and Life Science, Dalian Ocean University, Dalian 116023, China.ORCID 0009-0007-8381-4518

Funding

Dalian Ocean University JYTMS20230487
6 · The paper itself

Abstract

In recent years, chitosan oligosaccharide (COS) has demonstrated promising applications in enhancing the immune protective function of sea cucumbers. However, the immune-protective effect of COS on sea cucumber coelomocytes in vitro remains unclear. This study investigated the effect of COS on lipopolysaccharide (LPS)-stimulated inflammation in sea cucumber coelomocytes. First, we measured the effects of COS and LPS on the viability of coelomocytes. COS exhibited no toxic effects on sea cucumber coelomocytes. Furthermore, pre-incubating the coelomocytes with COS significantly improved coelomocytes' viability after LPS stimulation (

Indexed as

Apostichopus japonicuschitosan oligosaccharidecoelomocytesimmunoprotectionlipopolysaccharidetranscriptomic analysis

Identifiers

PMID41150293
PMCPMC12566613

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.