Evidence map›Paper›PMID 41150214›Full record

ArticleToxins2025

Protective Effect of Ethoxyquin and N-acetylcysteine on Biochemical and Pathological Changes Induced by Chronic Exposure to Aflatoxins in Laying Hens.

María Carolina de-Luna-López, Arturo Gerardo Valdivia-Flores, Teódulo Quezada-Tristán, Raúl Ortiz-Martínez, Erika Janet Rangel-Muñoz, Emmanuel Hernández-Valdivia, Esther Albarrán-Rodríguez, Elizabeth de Santiago-Díaz

Abstract read
In one paragraph

Article in Toxins, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

María Carolina de-Luna-LópezDepartamento de Ciencias Veterinarias, Centro de Ciencias Agropecuarias, Universidad Autónoma de Aguascalientes, Aguascalientes 20131, Mexico.
Arturo Gerardo Valdivia-FloresDepartamento de Ciencias Veterinarias, Centro de Ciencias Agropecuarias, Universidad Autónoma de Aguascalientes, Aguascalientes 20131, Mexico.ORCID 0000-0002-9354-0588
Teódulo Quezada-TristánDepartamento de Ciencias Veterinarias, Centro de Ciencias Agropecuarias, Universidad Autónoma de Aguascalientes, Aguascalientes 20131, Mexico.ORCID 0000-0002-3793-4582
Raúl Ortiz-MartínezDepartamento de Ciencias Veterinarias, Centro de Ciencias Agropecuarias, Universidad Autónoma de Aguascalientes, Aguascalientes 20131, Mexico.
Erika Janet Rangel-MuñozDepartamento de Ciencias Veterinarias, Centro de Ciencias Agropecuarias, Universidad Autónoma de Aguascalientes, Aguascalientes 20131, Mexico.ORCID 0000-0001-8321-6090
Emmanuel Hernández-ValdiviaDepartamento de Ciencias Veterinarias, Centro de Ciencias Agropecuarias, Universidad Autónoma de Aguascalientes, Aguascalientes 20131, Mexico.ORCID 0000-0001-8261-5129
Esther Albarrán-RodríguezDepartamento de Medicina Veterinaria, Centro Universitario de Ciencias Biológicas Agrícolas, Universidad de Guadalajara, Guadalajara, Jalisco 45110, Mexico.ORCID 0000-0003-0030-8630
Elizabeth de Santiago-DíazDepartamento de Ciencias Veterinarias, Centro de Ciencias Agropecuarias, Universidad Autónoma de Aguascalientes, Aguascalientes 20131, Mexico.

Funding

Autonomous University of Aguascalientes PIP/SA 25-1CONAHCYT 227916/209250
6 · The paper itself

Abstract

Aflatoxins (AFs) represent a major threat to poultry health and food safety due to their hepatotoxic, immunosuppressive, and carcinogenic effects. This study evaluated the chemoprotective potential of ethoxyquin (EQ) and N-acetylcysteine (NAC) in laying hens (80.8 and 33.3 mg/kg BW/d) exposed to chronic dietary AFs contamination (0.0-1.5 mg/kg). A total of 360 Hy-Line W36 Leghorn hens were monitored over 72 weeks using biochemical and histopathological analyses of liver and kidney tissues. NAC significantly (

Indexed as

AcetylcysteineAflatoxinsAntioxidantsEthoxyquinProtective AgentsAnimalsChickensFemaleGlutathioneGlutathione TransferaseKidneyLiverPoultry DiseasesAcetylcysteineAflatoxinsAntioxidantsEthoxyquinGlutathioneGlutathione TransferaseProtective Agentsaflatoxicosisglutathione S-transferaseliver pathologypoultryreduced glutathione

Identifiers

PMID41150214
PMCPMC12568094

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.