Evidence map›Paper›PMID 41150212›Full record

ArticleToxins2025

Mechanisms of Cellular Responses of the Natural Alkaloid Caulerpin and Its Similarities with the Lipid-Lowering Agent Fenofibrate in

Michela Panni, Marica Mezzelani, Maria Elisa Giuliani, Paola Nisi Cerioni, Alessandro Nardi, Ernesto Mollo, Francesco Regoli, Maura Benedetti, Stefania Gorbi

Abstract read
In one paragraph

Article in Toxins, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Michela PanniDipartimento di Scienze della Vita e dell'Ambiente, Università Politecnica delle Marche, Via Brecce Bianche, 60131 Ancona, Italy.
Marica MezzelaniDipartimento di Scienze della Vita e dell'Ambiente, Università Politecnica delle Marche, Via Brecce Bianche, 60131 Ancona, Italy.
Maria Elisa GiulianiAdvanced Technology Center for Aging Research and Geriatric Mouse Clinic (IRCCS-INRCA), 60121 Ancona, Italy.ORCID 0000-0002-7487-5171
Paola Nisi CerioniDipartimento di Scienze della Vita e dell'Ambiente, Università Politecnica delle Marche, Via Brecce Bianche, 60131 Ancona, Italy.
Alessandro NardiDipartimento di Scienze della Vita e dell'Ambiente, Università Politecnica delle Marche, Via Brecce Bianche, 60131 Ancona, Italy.ORCID 0000-0002-9978-1411
Ernesto MolloInstitute of Biomolecular Chemistry, National Research Council, 80078 Pozzuoli, Italy.ORCID 0000-0001-7379-1788
Francesco RegoliDipartimento di Scienze della Vita e dell'Ambiente, Università Politecnica delle Marche, Via Brecce Bianche, 60131 Ancona, Italy.
Maura BenedettiDipartimento di Scienze della Vita e dell'Ambiente, Università Politecnica delle Marche, Via Brecce Bianche, 60131 Ancona, Italy.
Stefania GorbiDipartimento di Scienze della Vita e dell'Ambiente, Università Politecnica delle Marche, Via Brecce Bianche, 60131 Ancona, Italy.ORCID 0000-0002-4232-2652

Funding

Ministero dell'università e della ricerca GA Nº 869178Ministero dell'università e della ricerca Project code CN_00000033; Concession Decree No. 1034 of 17 June 2022; National Biodiversity Future Center-NBFC
6 · The paper itself

Abstract

Marine-derived natural products have attracted increasing attention due to their promising pharmacological potential against various diseases. The present study investigated the hypolipidemic properties of the alkaloid caulerpin, a secondary metabolite of green algae of the genus

Indexed as

AlkaloidsFenofibrateHypolipidemic AgentsIndolesMytilusSpiro CompoundsAnimalsLipid MetabolismAlkaloidscaulerpinFenofibrateHypolipidemic AgentsIndolesSpiro Compoundscaulerpinfenofibratelipid metabolismmechanisms of actionmolecular responsesMytilus galloprovincialisredox homeostasis

Identifiers

PMID41150212
PMCPMC12567801

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.