Evidence map›Paper›PMID 41150152›Full record

ArticleVeterinary sciences2025

Combining Load-Close-Homogenize with Testing, Removal, and Rollover Strategies to Repopulate PRRSV Elimination Breeding Herds Using PRRSV-Positive Weaned Gilts.

Yulong Hu, Kangning Zhao, Guangqiang Wu, Haozhou Hong, Tian Xia, Zhicheng Liu, Yijuan Wang, Chunqing Sun, Chaosi Li, Zhendong Zhang and 1 more

Abstract read
In one paragraph

Article in Veterinary sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yulong HuBoehringer Ingelheim Animal Health (Shanghai) Co., Ltd., Shanghai 200000, China.
Kangning ZhaoMOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210000, China.
Guangqiang WuFujian Jinsheng Breeding Co., Ltd., Sanming 365000, China.
Haozhou HongGuangdong Tinoo's Food, Qingyuan 511500, China.
Tian XiaFujian YongCheng Breeding Technology Group Co., Ltd., Fuqing 350300, China.
Zhicheng LiuGuangdong Province Key Laboratory of Livestock Disease Prevention, Institute of Animal Health, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, China.
Yijuan WangZhangzhou Disease Prevention and Control Center, Zhangzhou 363000, China.
Chunqing SunBoehringer Ingelheim Animal Health (Shanghai) Co., Ltd., Shanghai 200000, China.
Chaosi LiBoehringer Ingelheim Animal Health (Shanghai) Co., Ltd., Shanghai 200000, China.ORCID 0009-0003-5438-3123
Zhendong ZhangJiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, College of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China.
Jianfeng ZhangGuangdong Province Key Laboratory of Livestock Disease Prevention, Institute of Animal Health, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, China.

Funding

Boehringer-Ingelheim 470049745
6 · The paper itself

Abstract

This study aimed to evaluate the effectiveness of combining load-close-homogenize (LCH), test and removal (T&R), and rollover strategies for PRRSV elimination in breeding herds using PRRSV-positive weaned gilts. Here, a novel strategy was explored for PRRSV elimination from more than 1500 weaned gilts, and we documented the process from PRRSV natural infection to elimination at the herd level. With LCH implementation, the herd achieved PRRSV-positive stability within 8 months. Consequently, by rolling in self-breeding PRRSV-naive gilts to replace PRRSV-positive weaned sows batch by batch, the time from being positive stable to negative was 13 months. A PRRSV-positive farm intending to retain its genes in its repopulate farrow to become a finished breeding farm can initiate PRRSV elimination from its weaned gilts; this will result in the first farrowing batch of piglets aged 8-10 weeks becoming PRRSV-negative after 8 months of herd closure. This approach offers a viable pathway for genetic retention and PRRSV elimination in breeding farms.

Indexed as

live virus inoculationload–close–homogenizePRRSV eliminationrollovertest and removalweaned gilt

Identifiers

PMID41150152
PMCPMC12567787

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.