ArticleVeterinary sciences2025
Assessment of the Relationship Between Bioexclusion Practices Applied in Wean-to-Harvest Sites and PRRS Outbreaks.
Article in Veterinary sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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14 authors.
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Abstract
Porcine reproductive and respiratory syndrome virus (PRRSV) is a significant cause of economic loss in the swine industry, yet its control remains challenging in wean-to-harvest sites. This prospective observational study followed 95 wean-to-harvest sites across six U.S. states for one production cycle. Sites were required to be PRRSV-negative or vaccinated with a modified live virus (MLV) and free of major coronaviruses. Outbreaks were defined as RT-qPCR-positive in unvaccinated sites or detection of ORF5 sequences distinct from the MLV strain. Biosecurity data were collected through a survey, and oral fluids were tested every four weeks. PRRS outbreaks occurred in 14/42 nurseries (33.3%), 8/12 wean-to-finish (66.7%), and 35/41 finishers (82.4%), with lineage 1C.5 most frequently detected. In univariate models, higher odds of outbreaks were associated with transporting pigs of unknown status (OR 9.80, 1.73-55.37), rendering (OR 6.47, 1.62-25.84), and employee cohabitation (OR 6.15, 1.51-25.09). Protective factors included exclusive pumping equipment (OR 0.07, 0.01-0.43) and overnight downtime for multi-site workers (OR 0.15, 0.04-0.56). In multivariable models, finisher sites (OR 17.47, 2.44-125.19) and greater swine site density within one mile (OR 1.62, 1.09-2.41) significantly increased outbreak odds. These results support targeted biosecurity practices, helping farmers and the swine industry reduce PRRS outbreaks.
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