Evidence map›Paper›PMID 41150117›Full record

ArticleVeterinary sciences2025

Multivariate Single-Step GWAS Reveals Pleiotropic Genomic Regions and Candidate Genes Associated with Male Scrotal Circumference and Female Fertility Traits in Retinta Beef Cattle.

Chiraz Ziadi, Rosa María Morales, María Ángeles Vargas-Pérez, Gabriel Anaya Calvo-Rubio, Sebastián Demyda-Peyrás, Antonio Molina

Abstract read
In one paragraph

Article in Veterinary sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chiraz ZiadiDepartment of Genetics, University of Córdoba, 14071 Córdoba, Spain.ORCID 0000-0002-1866-7028
Rosa María MoralesDepartment of Genetics, University of Córdoba, 14071 Córdoba, Spain.ORCID 0000-0003-2113-0608
María Ángeles Vargas-PérezDepartment of Genetics, University of Córdoba, 14071 Córdoba, Spain.ORCID 0009-0002-5134-5212
Gabriel Anaya Calvo-RubioDepartment of Genetics, University of Córdoba, 14071 Córdoba, Spain.ORCID 0000-0002-2145-6520
Sebastián Demyda-PeyrásDepartment of Genetics, University of Córdoba, 14071 Córdoba, Spain.ORCID 0000-0003-3286-2441
Antonio MolinaDepartment of Genetics, University of Córdoba, 14071 Córdoba, Spain.ORCID 0000-0002-9566-6600

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fertility is key for calf production. Direct selection for female fertility under field conditions is hindered by low accuracy and selection response. An alternative widely implemented is selection for scrotal circumference (SC), genetically correlated with daughter fertility. This study performed a genome-wide association study (GWAS) to identify genomic regions and candidate loci linked to SC and female fertility in Retinta cattle. A multivariate ssGBLUP was applied using SC records from 1061 bulls, fertility-related traits from 59,254 females and genotypes from 1230 animals using the Axiom™ Bovine Genotyping v3 Array (65k). The ssGWAS revealed 23 1-Mb windows explaining >1% of additive genetic variance for SC, one on chromosome 2 and 22 on chromosome 3. Within these windows, 198 regions spanning 118 protein-coding genes and 80 RNA genes were identified. Several genes, including

Indexed as

female fertility traitsGWASRetinta beef cattlescrotal circumferencessGBLUP

Identifiers

PMID41150117
PMCPMC12567842

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.