Evidence map›Paper›PMID 41149981›Full record

ArticleMembranes2025

Electrostatic Targeting of Cancer Cell Membrane Models by NA-CATH:ATRA-1-ATRA-1: A Biophysical Perspective.

Maria C Klaiss-Luna, Małgorzata Jemioła-Rzemińska, Marcela Manrique-Moreno, Kazimierz Strzałka

Abstract read
In one paragraph

Article in Membranes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Maria C Klaiss-LunaChemistry Institute, Faculty of Exact and Natural Sciences, University of Antioquia A.A 1226, Medellin 050010, Colombia.ORCID 0000-0002-0508-6486
Małgorzata Jemioła-RzemińskaFaculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, 30-387 Krakow, Poland.ORCID 0000-0001-7790-4831
Marcela Manrique-MorenoChemistry Institute, Faculty of Exact and Natural Sciences, University of Antioquia A.A 1226, Medellin 050010, Colombia.ORCID 0000-0002-2391-7343
Kazimierz StrzałkaFaculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, 30-387 Krakow, Poland.ORCID 0000-0002-8367-4865

Funding

Universidad de Antioquia 2024-66871
6 · The paper itself

Abstract

Breast cancer continues to be the leading cancer diagnosis among women worldwide, affecting populations in both industrialized and developing regions. Given the rising number of diagnosed cases each year, there is an urgent need to explore novel compounds with potential anticancer properties. One group of such candidates includes cationic peptides, which have shown promise due to their unique membrane-targeting mechanisms that are difficult for cancer cells to resist. This study presents an initial biophysical assessment of NA-CATH:ATRA-1-ATRA-1, a synthetic peptide modeled after NA-CATH, originally sourced from the venom of the Chinese cobra (

Indexed as

biophysical studiesbreast cancerdifferential scanning calorimetryFourier-transform infrared spectroscopypeptide–lipid interactions

Identifiers

PMID41149981
PMCPMC12566102

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.