Evidence map›Paper›PMID 41149860›Full record

ReviewJournal of personalized medicine2025

Inflammatory Phenotypes of Bronchiectasis.

Evangelia Koukaki, Georgia Papaiakovou, Argyri Klironomou, Efthymia Theofani, Andreas M Matthaiou, Adamantia Liapikou, Nektarios Anagnostopoulos, Grigorios Stratakos, Petros Bakakos, Nikoletta Rovina

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of personalized medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Evangelia Koukaki1st Respiratory Medicine Department of National and Kapodistrian University of Athens, Sotiria Chest Diseases Hospital, 11527 Athens, Greece.ORCID 0000-0002-9770-173X
Georgia Papaiakovou1st Respiratory Medicine Department of National and Kapodistrian University of Athens, Sotiria Chest Diseases Hospital, 11527 Athens, Greece.
Argyri Klironomou1st Respiratory Medicine Department of National and Kapodistrian University of Athens, Sotiria Chest Diseases Hospital, 11527 Athens, Greece.ORCID 0009-0005-3142-2948
Efthymia TheofaniCellular Immunology Laboratory, Center for Basic Research, Biomedical Research Foundation of the Academy of Athens, 11527 Athens, Greece.
Andreas M Matthaiou5th Respiratory Medicine Department, Sotiria Chest Diseases Hospital, 11527 Athens, Greece.ORCID 0000-0003-1941-0213
Adamantia Liapikou5th Respiratory Medicine Department, Sotiria Chest Diseases Hospital, 11527 Athens, Greece.
Nektarios Anagnostopoulos1st Respiratory Medicine Department of National and Kapodistrian University of Athens, Sotiria Chest Diseases Hospital, 11527 Athens, Greece.ORCID 0000-0003-4925-2332
Grigorios Stratakos1st Respiratory Medicine Department of National and Kapodistrian University of Athens, Sotiria Chest Diseases Hospital, 11527 Athens, Greece.ORCID 0000-0002-5861-3454
Petros Bakakos1st Respiratory Medicine Department of National and Kapodistrian University of Athens, Sotiria Chest Diseases Hospital, 11527 Athens, Greece.ORCID 0000-0001-9256-9656
Nikoletta Rovina1st Respiratory Medicine Department of National and Kapodistrian University of Athens, Sotiria Chest Diseases Hospital, 11527 Athens, Greece.ORCID 0000-0003-0138-5582

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bronchiectasis is a heterogeneous chronic airway disease traditionally viewed as neutrophil-driven. Emerging evidence demonstrates distinct complex inflammatory phenotypes influencing clinical outcomes, prognosis and therapeutic options. A narrative review was conducted, informed by a structured literature search on PubMed and Google Scholar databases, focusing on inflammatory phenotypes in bronchiectasis. Based on the prevalent cellular population, four distinct phenotypes can be described. The most common is the neutrophilic phenotype, which is associated with frequent

Indexed as

biomarkersbronchiectasisneutrophilic inflammationphenotypesprecision medicine

Identifiers

PMID41149860
PMCPMC12565519

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.