Evidence map›Paper›PMID 41149785›Full record

ArticleNeurology international2025

Cognitive, Functional, and Emotional Recovery in Patients with Stroke: A Multidimensional Prospective Analysis.

Emilio Rubén Pego Pérez, Lourdes Bermello López, Eva Gómez Fernández, María Del Rosario Marín Arnés, Mercedes Fernández Vázquez, Carlota Touza González, María Irene Núñez Hernández

Abstract read
In one paragraph

Article in Neurology international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Variability in Stroke Journeys: A Qualitative Study of Experiences of Persons With Stroke.Health expectations : an international journal of public participation in health care and health policy · 2026
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Emilio Rubén Pego PérezDepartament of Psychiatry, Radiology, Public Health, Nursing and Medicine, Faculty of Nursing, University of Santiago de Compostela, 15704 Santiago de Compostela, Spain.ORCID 0000-0001-5515-9172
Lourdes Bermello LópezNeurology and Neurosurgery of Lucus Augusti Hospital, 27003 Lugo, Spain.
Eva Gómez FernándezNeurology and Neurosurgery of Lucus Augusti Hospital, 27003 Lugo, Spain.
María Del Rosario Marín ArnésNeurology and Neurosurgery of Lucus Augusti Hospital, 27003 Lugo, Spain.ORCID 0009-0002-7418-0457
Mercedes Fernández VázquezNeurology and Neurosurgery of Lucus Augusti Hospital, 27003 Lugo, Spain.
Carlota Touza GonzálezGalician Health Service, Santiago de Compostela Hospital, 15704 Santiago de Compostela, Spain.
María Irene Núñez HernándezNeurology and Neurosurgery of Lucus Augusti Hospital, 27003 Lugo, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStroke is a major cerebrovascular disease characterized by disrupted cerebral blood flow, leading to neuronal damage and significant physical, cognitive, and emotional sequelae. While advancements in acute stroke management have improved survival rates, long-term complications such as cognitive impairment and depression continue to hinder recovery. This study addresses these dimensions within the context of ischemic stroke.

aimThe aim of this study was to analyze the cognitive status, functionality, and depressive symptoms in patients with ischemic stroke, exploring interrelations between cognitive, functional, and emotional outcomes to prioritize clinical interventions.

designThis was an analytical, observational, cohort, and prospective study.

methodsThe study included 81 subjects diagnosed with ischemic stroke admitted to the Neurology Department of Lucus Augusti University Hospital. Data were collected at three time points-admission, discharge, and follow-up-using validated instruments such as the National Institutes of Health Stroke Scale, Mini-Mental State Examination, Barthel Index, and Beck Depression Inventory. Statistical analyses included Spearman's correlation, Kruskal-Wallis, and Mann-Whitney tests.

resultsPatients with greater cognitive impairment at admission showed poorer functional recovery and higher depressive symptoms during follow-up. Depressive symptoms remained minimal in most cases, but correlations with cognitive and functional deficits were significant. NIHSS scores at admission strongly predicted both functional and emotional recovery, reinforcing its value in early prognosis and therapeutic planning.

conclusionsThis study highlights the importance of integrating cognitive, functional, and emotional dimensions into stroke care protocols to optimize patient recovery and improve long-term outcomes.

Indexed as

cognitive dysfunctiondepressionfunctional statusischemic strokemini mental state examinationMMSEsurveys and questionnairestissue plasminogen activatortransient ischemic attack

Identifiers

PMID41149785
PMCPMC12566684

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.