Evidence map›Paper›PMID 41149736›Full record

ArticleJournal of functional biomaterials2025

Developments and Assessments of Crude Tea Saponin-Incorporated Silica Nanoparticles for Their Bioactivity Improvement.

Tanrada Likitsatian, Pimpisid Koonyosying, Sittiruk Roytrakul, Patcharawan Srisilapanan, Somdet Srichairatanakool, Jetsada Ruangsuriya

Abstract read
In one paragraph

Article in Journal of functional biomaterials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tanrada LikitsatianDepartment of Biochemistry, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.ORCID 0009-0007-6390-6386
Pimpisid KoonyosyingDepartment of Biochemistry, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.ORCID 0000-0002-6119-7009
Sittiruk RoytrakulNational Center for Genetic Engineering and Biotechnology (BIOTEC), National Science and Technology Development Agency, Pathum Thani 12120, Thailand.ORCID 0000-0003-3696-8390
Patcharawan SrisilapananSchool of Dentistry, Phayao University, Phayao 56000, Thailand.ORCID 0000-0001-9407-7452
Somdet SrichairatanakoolDepartment of Biochemistry, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.ORCID 0000-0002-5706-8781
Jetsada RuangsuriyaDepartment of Biochemistry, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.ORCID 0000-0002-9891-8113

Funding

Faculty of Medicine Fund, Chiang Mai University 069/2566National Innovation Agency (Public Organization) of Thailand CE0201-04-65-12-0279National Science and Technology Development Agency (NSTDA) SCA-CO-2563-12031-TH
6 · The paper itself

Abstract

The use of saponins with biosurfactant, antioxidant, anti-inflammatory, and anti-cancer properties is limited by their toxicity and bioavailability. This study focused on the fabrication, characterization, and bioactivity of crude tea saponin (TS) and TS-incorporated silica nanoparticles (TSNPs). Our results showed that TS contained seven saponins and that TSNPs had an average diameter of 200-300 nm, a negative surface charge, and high polydispersity. Fourier Transform Infrared Spectroscopy (FTIR) revealed an incorporation bond of Si-O- and -OH controlling releasing behavior with t

Indexed as

bioavailability enhancementcrude tea saponincytotoxicity reductionoxidative stresssilica nanoparticles

Identifiers

PMID41149736
PMCPMC12565442

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.