Evidence map›Paper›PMID 41149730›Full record

ReviewJournal of functional biomaterials2025

Natural Polymers, Their Modifications and Composites with Synthetic Polymers for Tympanic Membrane Regeneration.

Roman O Shaikenov, Polina G Serbun, Jingran Zhang, Hao Wu, Zuobin Wang, Petr P Snetkov, Svetlana N Morozkina

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of functional biomaterials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Roman O ShaikenovInstitute of Advanced Data Transfer Systems, ITMO University, Kronverkskiy Prospekt, 49, Bldg. A, Saint Petersburg 197101, Russia.ORCID 0009-0005-1721-1044
Polina G SerbunInstitute of Advanced Data Transfer Systems, ITMO University, Kronverkskiy Prospekt, 49, Bldg. A, Saint Petersburg 197101, Russia.ORCID 0009-0004-8186-8342
Jingran ZhangMinistry of Education Key Laboratory for Cross-Scale Micro and Nano Manufacturing, Changchun University of Science and Technology, Changchun 130022, China.
Hao WuMinistry of Education Key Laboratory for Cross-Scale Micro and Nano Manufacturing, Changchun University of Science and Technology, Changchun 130022, China.
Zuobin WangMinistry of Education Key Laboratory for Cross-Scale Micro and Nano Manufacturing, Changchun University of Science and Technology, Changchun 130022, China.
Petr P SnetkovInstitute of Advanced Data Transfer Systems, ITMO University, Kronverkskiy Prospekt, 49, Bldg. A, Saint Petersburg 197101, Russia.ORCID 0000-0001-9949-5709
Svetlana N MorozkinaInstitute of Advanced Data Transfer Systems, ITMO University, Kronverkskiy Prospekt, 49, Bldg. A, Saint Petersburg 197101, Russia.ORCID 0000-0003-0122-0251

Funding

Russian Science Foundation 25-73-20141
6 · The paper itself

Abstract

The perforation of the tympanic membrane is a world-wide clinical problem resulting from trauma or infection and requiring effective regeneration methods. In recent years researchers have focused on natural polymers as promising materials for restoring the structure and function of the tympanic membrane. This review summarizes current advances in the use of natural polymers, such as silk fibroin, chitosan, hyaluronic acid, collagen, bacterial cellulose, alginates and others, for the treatment of tympanic membrane perforations. The key properties of these materials are discussed, including their biocompatibility, biodegradability, mechanical strength, and ability to support cell adhesion and proliferation. The review also covers the potential of natural polymers and their combinations in tympanic membrane regeneration and suggests the directions for future research.

Indexed as

bacterial cellulosebiocompatible compositescollageneardrumhyaluronic acidnatural polymerssilk fibrointympanic membrane

Identifiers

PMID41149730
PMCPMC12565031

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.