Evidence map›Paper›PMID 41149643›Full record

ArticleMetabolites2025

In Vivo Anti-Inflammatory Activity of Four Edible Cactaceae Flowers from Mexico.

Christian Alfredo Pensamiento-Niño, Alma Delia Hernández-Fuentes, Javier Añorve-Morga, Arturo Duarte-Sierra, Esther Ramírez-Moreno, Carolina Guadalupe Sosa-Gutiérrez, Deyanira Ojeda-Ramírez

Abstract read
In one paragraph

Article in Metabolites, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Christian Alfredo Pensamiento-NiñoÁrea Académica de Ciencias Agrícolas y Forestales, Instituto de Ciencias Agropecuarias, Universidad Autónoma del Estado de Hidalgo, Avenida Universidad 133, San Miguel Huatengo, Santiago Tulantepec de Lugo Guerrero 43775, Mexico.ORCID 0000-0003-0222-5919
Alma Delia Hernández-FuentesÁrea Académica de Ingeniería en Alimentos e Ingeniería Agroindustrial, Instituto de Ciencias Agropecuarias, Universidad Autónoma del Estado de Hidalgo, Avenida Universidad 133, San Miguel Huatengo, Santiago Tulantepec de Lugo Guerrero 43775, Mexico.ORCID 0000-0003-2592-6689
Javier Añorve-MorgaÁrea Académica de Química, Instituto de Ciencias Básicas e Ingeniería, Universidad Autónoma del Estado de Hidalgo, Mineral de la Reforma 42184, Mexico.ORCID 0000-0002-0076-1526
Arturo Duarte-SierraDepartment of Food Science and Horticultural Research Centre, Laval University, Québec, QC G1V 0A6, Canada.ORCID 0000-0002-8215-9597
Esther Ramírez-MorenoÁrea Académica de Nutrición, Instituto de Ciencias de la Salud, Universidad Autónoma del Estado de Hidalgo, Circuito Actopan Tilcuautla s/n, Ex hacienda La Concepción, San Agustin Tlaxiaca, Pachuca 42160, Mexico.ORCID 0000-0002-9928-8600
Carolina Guadalupe Sosa-GutiérrezÁrea Académica de Medicina Veterinaria y Zootecnia, Instituto de Ciencias Agropecuarias, Universidad Autónoma del Estado de Hidalgo, Avenida Universidad 133, San Miguel Huatengo, Santiago Tulantepec de Lugo Guerrero 43775, Mexico.ORCID 0000-0002-5109-4671
Deyanira Ojeda-RamírezÁrea Académica de Medicina Veterinaria y Zootecnia, Instituto de Ciencias Agropecuarias, Universidad Autónoma del Estado de Hidalgo, Avenida Universidad 133, San Miguel Huatengo, Santiago Tulantepec de Lugo Guerrero 43775, Mexico.ORCID 0000-0003-4649-2699

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesThe therapeutic properties of edible flowers are widely used to improve human health. The phenolic compounds present in edible flowers, such as phenols and flavonoids, among others, play an important role as effective antioxidant compounds against diseases related to oxidative stress. These compounds exhibit biological activities such as anti-ulcerogenic, antimicrobial, neuroprotective, anti-cancer, and anti-inflammatory properties. The objective of this study was to evaluate the in vivo anti-inflammatory activity of hydroethanolic extracts of four Mexican cacti flowers.

methodsA hydroethanolic extract was obtained via maceration for each cactus flower and evaluated using a model of edema induced in mouse ears by 12-

resultsAll of the hydroalcoholic flower extracts showed an anti-inflammatory effect. The greatest effect of inhibition of auricular edema (61.2 ± 4.23%) was observed in the group of mice treated with the Cardon extract at a dose of 3 mg/ear. This effect can be attributed to the main compounds detected by HPLC in the extract such as

conclusionsThis preliminary evidence supports further preclinical evaluation of the Cardon flower.

Indexed as

12-O-tetradecanoylphorbol-13-acetateanti-inflammatory activitybiological activityedible flowershydroethanolic extractphenolic compounds

Identifiers

PMID41149643
PMCPMC12565958

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.