Evidence map›Paper›PMID 41149626›Full record

ArticleMetabolites2025

Integrated Transcriptomic and Metabolomic Insights into Flavor-Related Metabolism in Grape Berries Across Cultivars and Developmental Stages.

Liping Huang, Linan Zhang, Min Wang, Yue Zhu, Zhili Xun, Xi Dai, Qifeng Zhao

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PubMed Full text at PMC Publisher
In one paragraph

Article in Metabolites, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Liping HuangPomology Institute, Shanxi Agricultural University, Jinzhong 030801, China.
Linan ZhangCollege of Horticulture, Shanxi Agricultural University, Jinzhong 030801, China.
Min WangPomology Institute, Shanxi Agricultural University, Jinzhong 030801, China.
Yue ZhuPomology Institute, Shanxi Agricultural University, Jinzhong 030801, China.
Zhili XunPomology Institute, Shanxi Agricultural University, Jinzhong 030801, China.
Xi DaiCollege of Horticulture, Shanxi Agricultural University, Jinzhong 030801, China.
Qifeng ZhaoPomology Institute, Shanxi Agricultural University, Jinzhong 030801, China.

Funding

the Key Technology R&D Program for Breeding of Characteristic and Superior Fruit Tree Varieties 202201140601027
6 · The paper itself

Abstract

backgroundFlavor quality in grape berries is shaped by complex metabolic and regulatory networks during development.

methodsIn this study, we integrated transcriptomic and LC-MS-based metabolomic analyses to investigate three cultivars ('Mei Xiangbao', 'Adena Rose', and 'Kyoho') at two ripening stages.

resultsA total of 491 differentially accumulated metabolites (DAMs) were identified, mainly lipids, organic acids, and heterocyclic compounds. Among them, 33 core metabolites, including LysoPCs, malic acid, and linalool derivatives, were closely linked to aroma, membrane remodeling, and polyphenol biosynthesis. Transcriptome integration revealed 29 transcription factors (TFs) such as AP2/ERF, MYB, and bHLH, which showed strong associations with key metabolites, suggesting their involvement in lipid remodeling and phenylpropanoid-related pathways.

conclusionsThese results provide new insights into the molecular regulation of grape flavor metabolism and highlight candidate genes and metabolites for improving berry sensory quality.

Indexed as

fruit developmentgrape berriesLC–MS metabolomicstranscription factorstranscriptome

Identifiers

PMID41149626
PMCPMC12566481

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