Evidence map›Paper›PMID 41149605›Full record

ArticleMarine drugs2025

New Polyketides and a Ferroptosis Inhibitor from the Marine-Derived Fungus

Jicheng Xiao, Peng Wu, Yan Zhang, Qi Lv, Yulang Chi, Wei Xu, Wenzhen Lin, Zhongbin Cheng

Abstract read
In one paragraph

Article in Marine drugs, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jicheng XiaoKey Laboratory of Tropical Biological Resources of Ministry of Education, School of Pharmaceutical Sciences, Hainan University, Haikou 570228, China.
Peng WuKey Laboratory of Tropical Biological Resources of Ministry of Education, School of Pharmaceutical Sciences, Hainan University, Haikou 570228, China.
Yan ZhangKey Laboratory of Tropical Biological Resources of Ministry of Education, School of Pharmaceutical Sciences, Hainan University, Haikou 570228, China.
Qi LvKey Laboratory of Tropical Biological Resources of Ministry of Education, School of Pharmaceutical Sciences, Hainan University, Haikou 570228, China.
Yulang ChiCollege of Oceanology and Food Science, Quanzhou Normal University, Quanzhou 362000, China.ORCID 0000-0002-0443-5189
Wei XuSchool of Basic Medical Sciences, YiChun University, Yichun 336000, China.
Wenzhen LinFujian Institute of Subtropical Botany, Xiamen 361006, China.ORCID 0000-0002-7517-6364
Zhongbin ChengKey Laboratory of Tropical Biological Resources of Ministry of Education, School of Pharmaceutical Sciences, Hainan University, Haikou 570228, China.

Funding

National Natural Science Foundation of China 82460683
6 · The paper itself

Abstract

As a driver of neurodegenerative disorders, ischemic injuries, and acute organ dysfunction, ferroptosis represents a therapeutic target, and its inhibition may provide novel therapies. In our ongoing efforts to discover ferroptosis inhibitors from fungal strains, chemical investigation of the strain

Indexed as

AscomycotaFerroptosisPolyketidesAnimalsAquatic OrganismsHumansMiceMolecular StructurePolyketidesalkaloidsDiaporthe searleiferroptosispolyketides

Identifiers

PMID41149605
PMCPMC12565626

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.