Evidence map›Paper›PMID 41149590›Full record

ArticleMarine drugs2025

Structural Elucidation and Antiviral Activity Evaluation of Novelly Synthesized Guaiazulene Derivatives.

Canling Cheng, Lei Hou, Xuli Tang, Guoqiang Li

Abstract read
In one paragraph

Article in Marine drugs, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Canling ChengCollege of Food Science and Pharmaceutical Engineering, Zaozhuang University, Zaozhuang 277160, China.
Lei HouCollege of Food Science and Pharmaceutical Engineering, Zaozhuang University, Zaozhuang 277160, China.
Xuli TangCollege of Chemistry and Chemical Engineering, Ocean University of China, Qingdao 266100, China.
Guoqiang LiKey Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China.ORCID 0000-0003-3223-4007

Funding

Doctoral Research Fund of Zaozhuang University 21/1020713National Key R&D Program of China 2024YFC2815900
6 · The paper itself

Abstract

A series of guaiazulene derivatives were efficiently synthesized by one-step reaction using guaiazulene as the substrate. Their structures were fully characterized by comprehensive spectroscopic methods, and their antiviral activities against influenza A (H1N1) virus were evaluated. Compounds

Indexed as

Antiviral AgentsAzulenesInfluenza A Virus, H1N1 SubtypeSesquiterpenes, GuaianeAnimalsDogsHumansInhibitory Concentration 50Madin Darby Canine Kidney CellsMicrobial Sensitivity TestsMolecular StructureMonocyclic SesquiterpenesRibavirinStructure-Activity RelationshipAntiviral AgentsAzulenesguaiazuleneMonocyclic SesquiterpenesRibavirinSesquiterpenes, Guaianeantiviral activitiesguaiazulene derivativesmarine natural products

Identifiers

PMID41149590
PMCPMC12565720

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.