Evidence map›Paper›PMID 41149573›Full record

ArticleMarine drugs2025

Cytotoxic Mechanism of Deep-Sea Fungus

Yaqin Fan, Wenhui Xiong, Yuting Qiu, Yang Li, Xin Liu, Peiqing He, Guian Huang

Abstract read
In one paragraph

Article in Marine drugs, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yaqin FanSchool of Life Sciences, Qingdao Agricultural University, Qingdao 266109, China.
Wenhui XiongSchool of Life Sciences, Qingdao Agricultural University, Qingdao 266109, China.
Yuting QiuSchool of Life Sciences, Qingdao Agricultural University, Qingdao 266109, China.
Yang LiSchool of Life Sciences, Qingdao Agricultural University, Qingdao 266109, China.
Xin LiuSchool of Life Sciences, Qingdao Agricultural University, Qingdao 266109, China.
Peiqing HeMNR Key Laboratory of Marine Eco-Environmental Science and Technology, First Institute of Oceanography, Ministry of Natural Resources, Qingdao 266061, China.
Guian HuangSchool of Life Sciences, Qingdao Agricultural University, Qingdao 266109, China.

Funding

National Key R&D Program of China 2022YFC2804600National Natural Science Foundation of China 42006096
6 · The paper itself

Abstract

This study investigated the potential of the deep-sea-derived fungal metabolite, chlorinated azaphilone compound chaetomugilin O, in the treatment of thyroid cancer. Chaetomugilin O was extracted from the fungus

Indexed as

Antineoplastic AgentsBenzopyransChaetomiumThyroid NeoplasmsApoptosisCell Line, TumorCell ProliferationDose-Response Relationship, DrugHumansMolecular Docking SimulationPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktReactive Oxygen SpeciesSignal TransductionAntineoplastic AgentsBenzopyransPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktReactive Oxygen SpeciesChaetomium globosumdeep-sea fungusmolecular dockingthyroid cancertranscriptomic

Identifiers

PMID41149573
PMCPMC12565306

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.