Evidence map›Paper›PMID 41149497›Full record

ArticleCurrent oncology (Toronto, Ont.)2025

Regional and Temporal Variation in Receipt of Gabapentinoid and SSRI/SNRI Therapy Among Older Cancer Survivors in the United States.

Amber Nguyen, Yong-Fang Kuo, Daoqi Gao, Mukaila Raji

Abstract read
In one paragraph

Article in Current oncology (Toronto, Ont.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Amber NguyenSchool of Medicine, University of Texas Medical Branch, Galveston, TX 77555, USA.
Yong-Fang KuoDepartment of Biostatistics & Data Science, University of Texas Medical Branch, Galveston, TX 77555, USA.ORCID 0000-0003-1927-0927
Daoqi GaoDepartment of Biostatistics & Data Science, University of Texas Medical Branch, Galveston, TX 77555, USA.ORCID 0009-0004-2603-9138
Mukaila RajiGeriatric Medicine Division, Department of Internal Medicine, University of Texas Medical Branch, Galveston, TX 77555, USA.

Funding

Pattern, Variation and Outcomes of Opioid Prescription in Older AdultsR01DA039192 · NIDA · UNIVERSITY OF TEXAS MED BR GALVESTON · PI KUO, YONG-FANG, RAJI, MUKAILA A · 2016 to 2023
$3.1M
Cancer Prevention and Research Institute of Texas RP210130NCI NIH HHS HHSN261201800009CNCI NIH HHS HHSN261201800009INCI NIH HHS HHSN261201800015CNCI NIH HHS HHSN261201800015INCI NIH HHS HHSN261201800032CNCI NIH HHS HHSN261201800032INIDA NIH HHS R01 DA039192
6 · The paper itself

Abstract

Opioids and benzodiazepines (BZD) are commonly prescribed for older cancer survivors with co-occurring pain and anxiety. The prescribing rate of gabapentinoids (GABA), Selective Serotonin Reuptake Inhibitors (SSRIs), and Serotonin-Norepinephrine Reuptake Inhibitors (SNRIs) in the general population has increased as opioid/BZD alternatives, but little is known on temporal/regional trends in use of these alternatives among older cancer survivors. A retrospective cohort study using SEER-Medicare data was conducted. Patients aged ≥ 66 years, diagnosed with breast, colorectal, prostate, or lung cancer as their first cancer diagnosis any time from 2000 to 2015 and who were alive more than 5 years after cancer diagnosis, were eligible for inclusion. Temporal trends varied by region (

Indexed as

Cancer SurvivorsGabapentinNeoplasmsSelective Serotonin Reuptake InhibitorsSerotonin and Noradrenaline Reuptake InhibitorsAgedAged, 80 and overAnalgesics, OpioidFemaleHumansMaleRetrospective StudiesUnited StatesAnalgesics, OpioidGabapentinSelective Serotonin Reuptake InhibitorsSerotonin and Noradrenaline Reuptake Inhibitorscancer survivorgabapentinpain managementSNRISSRI

Identifiers

PMID41149497
PMCPMC12563467

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.