Evidence map›Paper›PMID 41149480›Full record

ArticleCurrent oncology (Toronto, Ont.)2025

Baseline Characteristics of Individuals with Metastatic Cancer Enrolled in the Alberta Cancer Exercise Study and 12-Week Findings for Symptom-Related and Physical Fitness Measures.

Shirin M Shallwani, S Nicole Culos-Reed, Kerry S Courneya, Tanya Williamson, Christopher Sellar, Harold Lau, Anil Abraham Joy, Jacob C Easaw, Michelle Audoin, Edith Pituskin and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Current oncology (Toronto, Ont.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Shirin M ShallwaniFaculty of Rehabilitation Medicine, University of Alberta, 2-50 Corbett Hall, Edmonton, AB T6G 2G4, Canada.
S Nicole Culos-ReedFaculty of Kinesiology, University of Calgary, 2500 University Dr NW, Calgary, AB T2N 1N4, Canada.
Kerry S CourneyaFaculty of Kinesiology, Sport, and Recreation, University of Alberta, 1-113 University Hall, Edmonton, AB T6G 2H9, Canada.ORCID 0000-0002-9677-3918
Tanya WilliamsonFaculty of Kinesiology, University of Calgary, 2500 University Dr NW, Calgary, AB T2N 1N4, Canada.
Christopher SellarDepartment of Physical Therapy, University of Alberta, 2-50 Corbett Hall, Edmonton, AB T6G 2G4, Canada.
Harold LauDepartment of Oncology, University of Calgary, 3395 Hospital Drive NW, Calgary, AB T2N 5G2, Canada.ORCID 0000-0003-0947-933X
Anil Abraham JoyMedical Oncology, Cross Cancer Institute, Alberta Health Services, 11560 University Avenue, Edmonton, AB T6G 1Z2, Canada.
Jacob C EasawMedical Oncology, Cross Cancer Institute, Alberta Health Services, 11560 University Avenue, Edmonton, AB T6G 1Z2, Canada.ORCID 0000-0001-5270-1050
Michelle AudoinPatient Partner, Cancer Rehabilitation Clinic, University of Alberta; 2-50 Corbett Hall, Edmonton, AB T6G 2G4, Canada.
Edith PituskinFaculty of Nursing, University of Alberta, 3-141 Edmonton Clinic Health Academy, Edmonton, AB T6G 1C9, Canada.
Margaret L McNeelyDepartment of Physical Therapy, University of Alberta, 2-50 Corbett Hall, Edmonton, AB T6G 2G4, Canada.ORCID 0000-0003-4376-4847

Funding

Alberta Cancer Foundation 2019Alberta Innovates Cancer Research Prevention Opportunity 2016
6 · The paper itself

Abstract

Exercise has been found to be safe and beneficial for people with advanced cancers, but more research is needed to understand how best to design and implement exercise programming. The Alberta Cancer Exercise (ACE) study examines the effectiveness and implementation of a 12-week community-based exercise program in Alberta, Canada, for people diagnosed with cancer. Here, we describe the characteristics of individuals with metastatic cancer enrolled in the ACE program and report 12-week changes in self-reported and objective outcomes. Of 306 participants, 274 (89.5%) completed the 12-week study. Many participants were female (65.4%), with ≥1 comorbidity (71.9%), and on active cancer treatment (74.8%). Common cancer types included breast (33.7%), genitourinary (16.7%), and digestive (15.0%). Frequent sites of metastasis were bone (44.8%), liver (28.8%), and lung (25.8%). The mean exercise attendance rate was 73.6%. One exercise-related adverse event (0.3%) and one non-exercise-related adverse event (0.3%) occurred, both in individuals with brain metastases. Participants demonstrated strong interest and engagement in exercise, with significant improvements in weekly physical activity, symptoms, quality of life, and physical fitness. Greater benefits were found among subgroups of male participants, those not undergoing chemotherapy, and those receiving group personal training or virtual circuit training. A low rate of adverse events is anticipated.

Indexed as

Exercise TherapyNeoplasmsPhysical FitnessAdultAgedAlbertaExerciseFemaleHumansMaleMiddle AgedNeoplasm Metastasisadvanced canceradverse eventcommunity-basedexerciseimplementationmetastatic cancer

Identifiers

PMID41149480
PMCPMC12562936

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.