Evidence map›Paper›PMID 41149444›Full record

ArticleGels (Basel, Switzerland)2025

Multilayer pH-Responsive Hydrogels Fabricated via Two-Step Ionic Crosslinking: Towards Advanced Wound Dressing Materials.

Gianluca Ciarleglio, Virginia Clarizia, Elisa Toto, Maria Gabriella Santonicola

Abstract read
In one paragraph

Article in Gels (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Gianluca CiarleglioDepartment of Chemical Engineering Materials Environment, Sapienza University of Rome, Via del Castro, Laurenziano 7, 00161 Rome, Italy.ORCID 0000-0002-1029-8766
Virginia ClariziaDepartment of Chemical Engineering Materials Environment, Sapienza University of Rome, Via del Castro, Laurenziano 7, 00161 Rome, Italy.
Elisa TotoDepartment of Chemical Engineering Materials Environment, Sapienza University of Rome, Via del Castro, Laurenziano 7, 00161 Rome, Italy.ORCID 0000-0001-8394-328X
Maria Gabriella SantonicolaDepartment of Chemical Engineering Materials Environment, Sapienza University of Rome, Via del Castro, Laurenziano 7, 00161 Rome, Italy.ORCID 0000-0002-2736-8580

Funding

Ministero dell'università e della ricerca ECS 0000024 Rome Technopole, PNRR Mission 4 Component 2 Investment 1.5Sapienza University of Rome AR22419077A1DC91Sapienza University of Rome RM123188F46B2474
6 · The paper itself

Abstract

The design of hydrogel-based materials for wound care management requires the integration of multiple functionalities, including the capacity to maintain hydration, to prevent infection, and to adapt to the dynamic wound microenvironment. In this study, we fabricated innovative pH-reactive multilayer hydrogel patches based on ionically crosslinked alginate and incorporated with bioactive compounds, including Manuka honey, hyaluronic acid, and

Indexed as

alginate hydrogelburn carechitosan coatingmultilayerpH responsive

Identifiers

PMID41149444
PMCPMC12563005

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.