Evidence map›Paper›PMID 41149369›Full record

ArticleGels (Basel, Switzerland)2025

Biofunctional Polyvinyl Alcohol/Xanthan Gum/Gelatin Hydrogel Dressings Loaded with Curcumin: Antibacterial Properties and Cell Viability.

María José Rivera, Alejandro Cament, Manuel Ahumada, Teresa Corrales, Verónica García, Jesús L Pablos, Javiera Osorio, Giselle Ramos-González, Leslie Vargas-Saturno, Marcelo Ezquer and 1 more

Abstract read
In one paragraph

Article in Gels (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

María José RiveraLaboratorio Química de Biomateriales, Departamento de Ciencias del Ambiente, Facultad de Química y Biología, Universidad de Santiago de Chile (USACH), Santiago 9170022, Chile.
Alejandro CamentLaboratorio Química de Biomateriales, Departamento de Ciencias del Ambiente, Facultad de Química y Biología, Universidad de Santiago de Chile (USACH), Santiago 9170022, Chile.
Manuel AhumadaEscuela de Biotecnología, Facultad de Ciencias, Ingeniería y Tecnología, Universidad Mayor, Camino La Pirámide 5750, Santiago 8580745, Chile.ORCID 0000-0002-0589-3296
Teresa CorralesGrupo Fotoquímica de Polímeros, Instituto de Ciencia y Tecnología de Polímeros (CSIC), Juan de la Cierva 3, 28006 Madrid, Spain.ORCID 0000-0002-0171-2283
Verónica GarcíaDepartamento de Ciencia y Tecnología de los Alimentos, Universidad de Santiago de Chile, Alameda 3363, Estación Central, Santiago 9170022, Chile.ORCID 0000-0002-5312-925X
Jesús L PablosDepartamento Química en Ciencias Farmacéuticas, U.D Química Inorgánica y Bioinorgánica, Instituto de Investigación Sanitaria Hospital 12 de Octubre i + 12, Universidad Complutense de Madrid, Plaza Ramón y Cajal s/n, 28040 Madrid, Spain.ORCID 0000-0001-8504-8836
Javiera OsorioCentro de Medicina Regenerativa, Facultad de Medicina, Clínica Alemana-Universidad del Desarrollo, Santiago 7610658, Chile.
Giselle Ramos-GonzálezCentro de Medicina Regenerativa, Facultad de Medicina, Clínica Alemana-Universidad del Desarrollo, Santiago 7610658, Chile.
Leslie Vargas-SaturnoCentro de Medicina Regenerativa, Facultad de Medicina, Clínica Alemana-Universidad del Desarrollo, Santiago 7610658, Chile.
Marcelo EzquerCentro de Medicina Regenerativa, Facultad de Medicina, Clínica Alemana-Universidad del Desarrollo, Santiago 7610658, Chile.
J Andrés OrtizLaboratorio Química de Biomateriales, Departamento de Ciencias del Ambiente, Facultad de Química y Biología, Universidad de Santiago de Chile (USACH), Santiago 9170022, Chile.ORCID 0000-0002-3142-9470

Funding

Agencia Nacional de Investigación y Desarrollo FONDECYT 11230657Agencia Nacional de Investigación y Desarrollo FONDECYT 1241229Fondef IDeA I+D 24I10119Ministerio de Ciencia, Innovación y Universidades Project Ref. PID2021-124926NB-I00Vicerrectoría de Investigación, Innovación y Creación POSTDOC_DICYT, Código 022541ON_Postdoc
6 · The paper itself

Abstract

This study explores the development of biocompatible hydrogel dressings incorporating curcumin as an alternative antibacterial agent. In this context, hydrogels were prepared using polyvinyl alcohol, xanthan gum, gelatin, and curcumin as a therapeutic component. FTIR spectroscopy confirmed the successful incorporation of curcumin into the hydrogel matrix, while release profiles demonstrated sustained release. Mechanical testing indicated that xanthan gum reduced elongation and strength in hydrogels, while the combination of xanthan gum and gelatin increased stiffness without loss of elasticity. Curcumin had no major effect on the tensile and rheological properties, preserving the structural integrity of the hydrogels. The hydrogels demonstrated antibacterial activity against

Indexed as

antibacterial activitycurcumincytocompatibilityhydrogelMRSA

Identifiers

PMID41149369
PMCPMC12562834

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.