ArticleBiosensors2025
A Highly Sensitive Fluorescent Sensor Based on Carbon Dots and Gold Nanoparticles for Carbaryl Through the Inner Filter Effect.
Article in Biosensors, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
A highly sensitive fluorescent sensing platform was successfully constructed through carbon dots (CDs) and gold nanoparticles (AuNPs) for the specific detection of carbaryl pesticide. Because of the overlap between the fluorescence emission spectrum of CDs and the ultraviolet (UV) absorption spectrum of AuNPs, the fluorescence intensity of CDs exhibited a remarkable decrease in the presence of AuNPs, which was primarily attributed to the inner filter effect (IFE). Acetylcholinesterase (AChE), as a crucial hydrolase in the cholinergic system, can efficiently catalyze the substrate acetylthiocholine iodide (ATChI), leading to the formation of thiocholine. Due to the fact that thiocholine exhibited a positive charge and contained a thiol (-SH), the introduction of thiocholine resulted in the aggregation of AuNPs via gold-thiol bonding and electrostatic interactions. Subsequently, the fluorescence of CDs was restored as the inner filter effect between CDs and AuNPs was alleviated. In addition, carbaryl exerted a significant inhibitory effect on the activity of AChE, impeding the generation of thiocholine and the aggregation of AuNPs, thereby maintaining the fluorescence of CDs quenched. Under the optimal analytical conditions, the detection range of carbaryl is from 0.1 to 200 ng/mL with a detection limit (LOD) of 0.05 ng/mL (S/N = 3). The proposed fluorescent sensor was successfully employed for the detection of carbaryl in strawberry samples with recoveries in the range of 97.5%-101.1%, with the relative standard deviation (RSD) less than 5%.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.