Evidence map›Paper›PMID 41149338›Full record

ArticleBiosensors2025

Universal Platform Based on Carbon Nanotubes Functionalised with Carboxylic Acid Groups for Multi-Analyte Enzymatic Biosensing.

Edmundas Lukoševičius, Julija Kravčenko, Grėta Mikėnaitė, Augustas Markevičius, Gintautas Bagdžiūnas

Abstract read
In one paragraph

Article in Biosensors, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Edmundas LukoševičiusGroup of Supramolecular Analysis and Bioelectronics, Institute of Biochemistry at Life Sciences Centre, Vilnius University, Saulėtekio av. 7, LT-10257 Vilnius, Lithuania.ORCID 0009-0009-0102-3988
Julija KravčenkoGroup of Supramolecular Analysis and Bioelectronics, Institute of Biochemistry at Life Sciences Centre, Vilnius University, Saulėtekio av. 7, LT-10257 Vilnius, Lithuania.
Grėta MikėnaitėGroup of Supramolecular Analysis and Bioelectronics, Institute of Biochemistry at Life Sciences Centre, Vilnius University, Saulėtekio av. 7, LT-10257 Vilnius, Lithuania.
Augustas MarkevičiusGroup of Supramolecular Analysis and Bioelectronics, Institute of Biochemistry at Life Sciences Centre, Vilnius University, Saulėtekio av. 7, LT-10257 Vilnius, Lithuania.ORCID 0009-0009-4368-627X
Gintautas BagdžiūnasGroup of Supramolecular Analysis and Bioelectronics, Institute of Biochemistry at Life Sciences Centre, Vilnius University, Saulėtekio av. 7, LT-10257 Vilnius, Lithuania.ORCID 0000-0002-9924-6902

Funding

Lietuvos Mokslo Taryba P-ITP-25-11
6 · The paper itself

Abstract

This work presents the development of carbon nanotubes functionalised with carboxylic acid groups (CNT-COOH) as an oxygen-sensitive electrochemical platform for parallel multi-analyte enzymatic biosensing. The platform was constructed by depositing carboxylic-acid-functionalised single-walled carbon nanotubes covalently onto nanostructured gold electrodes modified with a self-assembled monolayer of 4-aminothiophenol. Atomic force microscopy characterization revealed that the nanotubes attached via their ends to the surface and had a predominantly horizontal orientation. Glucose oxidase, lactate oxidase, glutamate oxidase, and tyrosinase were immobilised onto the electrodes to create selective biosensor for lactate, glucose, glutamate, and dopamine, respectively. A key finding is that incorporating catalase significantly extends the linear detection range for analytes by mitigating the accumulation of hydrogen peroxide. The resulting multifunctional biosensor demonstrated its capability for the simultaneous and independent measurement of glucose, lactate as the key bioanalytes under uniform conditions in blood plasma samples, highlighting its potential for applications in health and food technologies.

Indexed as

Biosensing TechniquesCarboxylic AcidsNanotubes, CarbonAmino Acid OxidoreductasesDopamineElectrodesEnzymes, ImmobilizedGlucoseGlucose OxidaseGlutamic AcidLactic AcidMixed Function OxygenasesMonophenol MonooxygenaseAmino Acid OxidoreductasesCarboxylic AcidsDopamineEnzymes, ImmobilizedGlucoseGlucose OxidaseGlutamic Acidlactate 2-monooxygenaseLactic AcidL-glutamate oxidaseMixed Function OxygenasesMonophenol MonooxygenaseNanotubes, Carboncarbon nanotubeelectrochemical platformenzymatic biosensoroxygen-sensitive electrode

Identifiers

PMID41149338
PMCPMC12563482

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.