Evidence map›Paper›PMID 41149328›Full record

ReviewBiosensors2025

Recent Advances in Electrochemical Sensors for the Detection of Anti-Inflammatory and Antibiotic Drugs: A Comprehensive Review.

Gisele Afonso Bento Mello, Stephen Rathinaraj Benjamin, Fábio de Lima, Rosa F Dutra

Abstract readReview
In one paragraph

Review in Biosensors, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Magnetically active MnFeNanoscale advances · 2026
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Gisele Afonso Bento MelloCurso de Licenciatura em Química, Instituto de Ciências da Educação (ICED), Universidade Federal do Oeste do Pará (UFOPA), Avenida Marechal Rondon, s/n, Caranazal, Santarém 68040-070, PA, Brazil.ORCID 0000-0001-7815-9327
Stephen Rathinaraj BenjaminLaboratory of Behavioral Neuroscience, Drug Research and Development Center (NPDM), Department of Physiology and Pharmacology, Federal University of Ceará (UFC), Coronel Nunes de Melo 1127, Porangabussu, Fortaleza 60430-270, CE, Brazil.ORCID 0000-0001-6049-2156
Fábio de LimaPostgraduate Program in Health and Development in the Central-West Region of Brazil, Federal University of Mato Grosso do Sul (UFMS), Campo Grande 79070-900, MS, Brazil.
Rosa F DutraBiomedical Engineering Laboratory, Department of Biomedical Engineering, Federal University of Pernambuco, Avenida Professor Moraes Rego, 1235, Recife 50670-901, PE, Brazil.ORCID 0000-0001-8314-4218

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Electrochemical sensors have emerged as powerful analytical tools for the detection of anti-inflammatory and antibiotic drugs due to their high sensitivity, rapid response, and cost-effectiveness compared to conventional chromatographic and spectrophotometric methods. This review highlights recent advances in electrode materials, surface modification strategies, and signal amplification approaches for quantifying nonsteroidal anti-inflammatory drugs (NSAIDs) and various antibiotic classes, including sulfonamides, tetracyclines, macrolides, and quinolones. Particular attention is given to nanostructured carbon-based materials, metal nanoparticles, and polymer composites that enhance electron transfer, improve selectivity, and lower limits of detection (LODs). The analytical performance of different electrochemical techniques such as cyclic voltammetry, differential pulse voltammetry, and square-wave voltammetry is critically compared across various drug targets. Trends indicate that hybrid nanomaterial-modified electrodes consistently achieve sub-micromolar detection limits in biological and environmental samples, offering potential for point-of-care diagnostics and environmental monitoring. Current challenges include improving sensor stability, mitigating fouling effects, and ensuring reproducibility in complex matrices. Future research should focus on integrated, miniaturized sensing platforms capable of multiplex detection, paving the way for rapid, portable, and sustainable analytical solutions in pharmaceutical and biomedical applications.

Indexed as

Anti-Bacterial AgentsAnti-Inflammatory AgentsAnti-Inflammatory Agents, Non-SteroidalBiosensing TechniquesElectrochemical TechniquesElectrodesHumansAnti-Bacterial AgentsAnti-Inflammatory AgentsAnti-Inflammatory Agents, Non-Steroidalantibioticsdrugs detectionelectrochemical sensorNSAIDs

Identifiers

PMID41149328
PMCPMC12563010

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.