Evidence map›Paper›PMID 41149304›Full record

ArticleBiosensors2025

Application of the Combined QCM-D/LSPR Aptasensor for Penicillin G Detection.

Sandro Spagnolo, Kiran Sontakke, Lukas Dubbert, Matthias Urban, Tomas Lednicky, Andrea Csaki, Katrin Wondraczek, Wolfgang Fritzsche, Tibor Hianik

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biosensors, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sandro SpagnoloFaculty of Mathematics, Physics and Informatics, Comenius University, Mlynska Dolina F1, 84248 Bratislava, Slovakia.
Kiran SontakkeFaculty of Mathematics, Physics and Informatics, Comenius University, Mlynska Dolina F1, 84248 Bratislava, Slovakia.
Lukas DubbertLeibniz Institute of Photonic Technology (Leibniz-IPHT), A. Einstein Str. 9, 07745 Jena, Germany.
Matthias UrbanLeibniz Institute of Photonic Technology (Leibniz-IPHT), A. Einstein Str. 9, 07745 Jena, Germany.
Tomas LednickyLeibniz Institute of Photonic Technology (Leibniz-IPHT), A. Einstein Str. 9, 07745 Jena, Germany.
Andrea CsakiLeibniz Institute of Photonic Technology (Leibniz-IPHT), A. Einstein Str. 9, 07745 Jena, Germany.ORCID 0000-0002-2414-4100
Katrin WondraczekLeibniz Institute of Photonic Technology (Leibniz-IPHT), A. Einstein Str. 9, 07745 Jena, Germany.ORCID 0000-0002-6268-9136
Wolfgang FritzscheLeibniz Institute of Photonic Technology (Leibniz-IPHT), A. Einstein Str. 9, 07745 Jena, Germany.ORCID 0000-0002-8376-676X
Tibor HianikFaculty of Mathematics, Physics and Informatics, Comenius University, Mlynska Dolina F1, 84248 Bratislava, Slovakia.ORCID 0000-0002-5906-0548

Funding

European Commision 101109232European Commission 101007299European Commission 825051German Academic Exchange Service DAAD PPPThe Science Agency VEGA 1/0445/23
6 · The paper itself

Abstract

Penicillin G (PEN) is a widely used antibiotic for treating microbial infections. However, its extensive use in veterinary medicine can lead to accumulation in animal-derived products, particularly milk and meat. This highlights the urgent need for rapid and sensitive antibiotic detection methods. In this study, we employed DNA aptamers for the detection of PEN and for the analysis of aptamer specificity using a combined approach based on quartz crystal microbalance with dissipation monitoring (QCM-D) and localized surface plasmon resonance (LSPR). QCM-D measures changes in resonant frequency, Δ

Indexed as

Aptamers, NucleotideBiosensing TechniquesPenicillin GQuartz Crystal Microbalance TechniquesSurface Plasmon ResonanceAnti-Bacterial AgentsGoldLimit of DetectionMetal NanoparticlesAnti-Bacterial AgentsAptamers, NucleotideGoldPenicillin GbiosensorDNA aptamerlocalized surface plasmon resonancepenicillin Gquartz crystal microbalance

Identifiers

PMID41149304
PMCPMC12564596

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.