Evidence map›Paper›PMID 41149284›Full record

ArticleJournal of cardiovascular development and disease2025

Risk Factors for Reintervention in Children with Subvalvular Aortic Stenosis: A 20-Year Single-Center Study.

Jelena Hubrechts, Alessandra Zanfardino, Catherine Barrea, Thierry Detaille, Alain Poncelet

Abstract read
In one paragraph

Article in Journal of cardiovascular development and disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jelena HubrechtsDivision of Congenital and Pediatric Cardiology, Department of Pediatrics, University Hospitals Saint-Luc, Université Catholique de Louvain, Avenue Hippocrate 10, B-1200 Brussels, Belgium.ORCID 0000-0001-6719-2746
Alessandra ZanfardinoDepartment of Cardiovascular and Thoracic Surgery, University Hospitals Saint-Luc, Université Catholique de Louvain, B-1200 Brussels, Belgium.
Catherine BarreaDivision of Congenital and Pediatric Cardiology, Department of Pediatrics, University Hospitals Saint-Luc, Université Catholique de Louvain, Avenue Hippocrate 10, B-1200 Brussels, Belgium.
Thierry DetailleDepartment of Pediatric Intensive Care Unit, University Hospitals Saint-Luc, Université Catholique de Louvain, B-1200 Brussels, Belgium.ORCID 0000-0003-0372-578X
Alain PonceletDepartment of Cardiovascular and Thoracic Surgery, University Hospitals Saint-Luc, Université Catholique de Louvain, B-1200 Brussels, Belgium.ORCID 0000-0002-3220-2681

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Subvalvular aortic stenosis (SAS) is a frequent cause of left ventricular outflow tract (LVOT) obstruction in children. Surgical resection is the standard treatment, yet recurrence requiring reintervention remains a significant concern. We aim to identify risk factors associated with surgical reintervention. This retrospective study included 76 patients under 18 years who underwent surgical resection for SAS between 2000 and 2020. Preoperative, intraoperative, and postoperative data were analyzed. The mean age at initial surgery was 5.8 years. In addition to subaortic membrane resection, myomectomy was performed in 73.7% of patients. Reintervention was required in 13.1% of cases, with reintervention-free survival at 5 and 10 years of 93.4% and 89.5%, respectively. Significant predictors of reintervention included younger age and shorter stature at surgery. Myomectomy reduced postoperative gradients but was not protective against recurrence and was associated with a higher rate of conductive disorders requiring pacemakers. While surgical resection of SAS is associated with excellent survival, recurrence remains a concern, especially in younger patients and those with tunnel-like lesions. Individualized surgical planning is essential to balance recurrence risk with potential complications.

Indexed as

childrenrisk factors of recurrencesubvalvular aortic stenosissurgical resection

Identifiers

PMID41149284
PMCPMC12565481

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.