Evidence map›Paper›PMID 41149259›Full record

ArticleJournal of cardiovascular development and disease2025

Hypertrabeculation in Olympic Athletes: Advanced LV Function Analysis by CMR.

Alessandro Spinelli, Sara Monosilio, Giuseppe Di Gioia, Gianni Pedrizzetti, Giovanni Tonti, Cosimo Damiano Daniello, Maria Rosaria Squeo, Antonio Pelliccia, Viviana Maestrini

Abstract read
In one paragraph

Article in Journal of cardiovascular development and disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Alessandro SpinelliInstitute of Sports Medicine and Science, Italian National Olympic Committee, 00197 Rome, Italy.ORCID 0009-0005-2446-0284
Sara MonosilioInstitute of Sports Medicine and Science, Italian National Olympic Committee, 00197 Rome, Italy.ORCID 0000-0001-5960-7980
Giuseppe Di GioiaInstitute of Sports Medicine and Science, Italian National Olympic Committee, 00197 Rome, Italy.ORCID 0000-0002-9158-5440
Gianni PedrizzettiDepartment of Engineering and Architecture, University of Trieste, 34127 Trieste, Italy.ORCID 0000-0003-2886-7653
Giovanni TontiCardiology Division, 'G. D'Annunzio' University, 66100 Chieti, Italy.ORCID 0009-0001-5890-4358
Cosimo Damiano DanielloInstitute of Sports Medicine and Science, Italian National Olympic Committee, 00197 Rome, Italy.
Maria Rosaria SqueoInstitute of Sports Medicine and Science, Italian National Olympic Committee, 00197 Rome, Italy.
Antonio PellicciaInstitute of Sports Medicine and Science, Italian National Olympic Committee, 00197 Rome, Italy.
Viviana MaestriniInstitute of Sports Medicine and Science, Italian National Olympic Committee, 00197 Rome, Italy.ORCID 0000-0002-3225-8378

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Left ventricular (LV) hypertrabeculation is increasingly recognized as a phenotype that may reflect physiological adaptation, particularly in athletes exposed to chronic overload, although its functional relevance remains uncertain. This study evaluated the prevalence of excessive trabeculation and its physiological correlation with LV remodeling. We conducted a single-center, cross-sectional study involving 320 Olympic-level athletes without cardiovascular disease. All underwent cardiac magnetic resonance (CMR). Hypertrabeculation was defined by the Petersen criteria. Athletes meeting these criteria were classified as hypertrabeculated and compared with non-hypertrabeculated matched for age, sex, and sport category. LV morphology, function, strain parameters, and hemodynamic forces (HDFs) were analyzed. Hypertrabeculation was identified in 9% of the cohort. No significant differences were observed between groups for training exposure (

Indexed as

athlete’s heartCMRhemodynamic forceshypertrabeculationstrain

Identifiers

PMID41149259
PMCPMC12565303

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.