Evidence map›Paper›PMID 41149095›Full record

ReviewDentistry journal2025

Vitamin D in Peri-Implant and Periodontal Tissue.

Felipe de Souza Duarte, Nathália Dantas Duarte, Gabriel Mulinari-Santos, Paula Buzo Frigério, Roberta Okamoto, Rogerio Leone Buchaim, Daniela Vieira Buchaim, João Paulo Mardegan Issa

Abstract readReview
In one paragraph

Review in Dentistry journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Felipe de Souza DuarteDepartment of Diagnosis and Surgery, Araçatuba School of Dentistry (FOA-UNESP), São Paulo State University, Araçatuba 16015-050, Brazil.ORCID 0000-0001-9451-6873
Nathália Dantas DuarteDepartment of Diagnosis and Surgery, Araçatuba School of Dentistry (FOA-UNESP), São Paulo State University, Araçatuba 16015-050, Brazil.ORCID 0000-0002-5207-6360
Gabriel Mulinari-SantosDepartment of Basic Sciences, Araçatuba School of Dentistry (FOA-UNESP), São Paulo State University, Araçatuba 16015-050, Brazil.
Paula Buzo FrigérioDepartment of Diagnosis and Surgery, Araçatuba School of Dentistry (FOA-UNESP), São Paulo State University, Araçatuba 16015-050, Brazil.ORCID 0000-0002-5012-5093
Roberta OkamotoDepartment of Basic Sciences, Araçatuba School of Dentistry (FOA-UNESP), São Paulo State University, Araçatuba 16015-050, Brazil.ORCID 0000-0002-6773-6966
Rogerio Leone BuchaimDepartment of Biological Sciences, Bauru School of Dentistry (FOB-USP), University of São Paulo, Bauru 17012-901, Brazil.ORCID 0000-0002-5881-2218
Daniela Vieira BuchaimGraduate Program in Anatomy of Domestic and Wild Animals, School of Veterinary Medicine and Animal Sciences, University of São Paulo (FMVZ-USP), São Paulo 05508-270, Brazil.ORCID 0000-0002-9914-1262
João Paulo Mardegan IssaDepartment of Basic and Oral Biology, Ribeirão Preto School of Dentistry (FORP-USP), University of São Paulo, Ribeirão Preto 14040-904, Brazil.ORCID 0000-0002-1056-0795

Funding

CNPq The National Council for Scientific and Technological Development/Conselho Nacional de Desenvolvimento Científico e Tecnológico 302545/2025-5CNPq The National Council for Scientific and Technological Development/Conselho Nacional de Desenvolvimento Científico e Tecnológico 302999/2024-8
6 · The paper itself

Abstract

This review aims to provide an overview of the role of vitamin D in peri-implant and periodontal tissue. Electronic searches were carried out of the PubMed/Medline database. Since this is a narrative review, no systematic search, meta-analysis, or statistical analysis was performed. Vitamin D plays a crucial role in bone balance and metabolism, contributing to reducing early implant failure and improving dental implant osseointegration. Vitamin D deficiency poses a challenge to clinical outcomes, and its supplementation can be an effective alternative to overcome this limitation. The results reported in this article show that vitamin D application on implants can improve the osseointegration, bone-to-implant contact, implant stability, and bone density. Moreover, vitamin D supplementation can increase RUNX2, ALP, OPN, and OCN expression, contributing to periodontal tissue health and its regeneration. Together, findings provide an overview of these topics and present future perspectives for clinical practice in dentistry.

Indexed as

bone regenerationcalcitrioldentistryosseointegrationperi-implantitisperiodontal diseasesreviewvitamin D

Identifiers

PMID41149095
PMCPMC12564239

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.