Evidence map›Paper›PMID 41149025›Full record

ArticleEntropy (Basel, Switzerland)2025

Noise Robustness of Transcript-Based Estimators for Properties of Interactions.

Manuel Adams, Klaus Lehnertz

Abstract read
In one paragraph

Article in Entropy (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Manuel AdamsDepartment of Epileptology, University Hospital Bonn, Venusberg-Campus 1, 53127 Bonn, Germany.ORCID 0009-0008-8304-0273
Klaus LehnertzDepartment of Epileptology, University Hospital Bonn, Venusberg-Campus 1, 53127 Bonn, Germany.ORCID 0000-0002-5529-8559

Funding

Deutsche Forschungsgemeinschaft LE 660/10-1
6 · The paper itself

Abstract

We investigate the robustness of transcript-based estimators for properties of interactions against various types of noise, ranging from colored noise to isospectral noise. We observe that all estimators are sensitive to symmetric and asymmetric contamination at signal-to-noise ratios that are orders of magnitude higher than those typically encountered in real-world applications. While different coupling regimes can still be distinguished and characterized sufficiently well, the strong impact of noise on the estimator for the direction of interaction can lead to severe misinterpretations of the underlying coupling structure.

Indexed as

colored noisecomplexitydirectionalityinteractionsordinal patternssynchronizationtranscripts

Identifiers

PMID41149025
PMCPMC12563163

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.