Evidence map›Paper›PMID 41148854›Full record

ReviewCells2025

Alcohol Consumption and Cervical Carcinogenesis: Time to Draw Conclusions.

Vivek K Kashyap, Divya B Kenchappa, Ajay K Singh, Bhupesh Singh, Murali M Yallapu, Everardo Cobos, Subhash C Chauhan

Abstract readReview
In one paragraph

Review in Cells, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Vivek K KashyapDivision of Cancer Immunology and Microbiology, Medicine and Oncology Integrated Service Unit, School of Medicine, University of Texas Rio Grande Valley, McAllen, TX 78504, USA.
Divya B KenchappaDepartment of Pharmaceutical Sciences, University of Tennessee Health Science Center, Memphis, TN 38163, USA.
Ajay K SinghDepartment of Pediatric-Pulmonology, University of Tennessee Health Science Center, Le Bonheur Children's Hospital, Memphis, TN 38103, USA.
Bhupesh SinghSchool of Applied Sciences, OM Sterling Global University, Hisar 125001, Haryana, India.
Murali M YallapuDivision of Cancer Immunology and Microbiology, Medicine and Oncology Integrated Service Unit, School of Medicine, University of Texas Rio Grande Valley, McAllen, TX 78504, USA.ORCID 0000-0002-0073-8828
Everardo CobosDepartment of Medicine, School of Medicine, University of Texas Rio Grande Valley, McAllen, TX 78504, USA.
Subhash C ChauhanDivision of Cancer Immunology and Microbiology, Medicine and Oncology Integrated Service Unit, School of Medicine, University of Texas Rio Grande Valley, McAllen, TX 78504, USA.

Funding

Rio Grande Valley Cancer Health Disparity Research CenterU54MD019970 · NIMHD · UNIVERSITY OF TEXAS RIO GRANDE VALLEY · PI Deepu George · 2024 to 2026
$15.0M
MUC13 Mucin in Colorectal Cancer Health DisparityR01CA204552 · NCI · UNIVERSITY OF TEXAS RIO GRANDE VALLEY · PI CHAUHAN, SUBHASH C. · 2016 to 2020
$1.7M
Development of Targeted Nanotechnology Platform for Pancreatic CancerR01CA206069 · NCI · UNIVERSITY OF TEXAS RIO GRANDE VALLEY · PI CHAUHAN, SUBHASH C. · 2016 to 2021
$1.7M
Targeted Nanotherapy for Pancreatic CancerR01CA210192 · NCI · UNIVERSITY OF TEXAS RIO GRANDE VALLEY · PI CHAUHAN, SUBHASH C. · 2016 to 2021
$1.7M
miR-205 Nanoparticle system circumvents docetaxel resistance in prostate cancerSC1GM139727 · NIGMS · UNIVERSITY OF TEXAS RIO GRANDE VALLEY · PI YALLAPU, MURALI MOHAN · 2021 to 2024
$1.5M
NCI NIH HHS R01 CA204552NCI NIH HHS R01 CA206069NCI NIH HHS R01 CA210192NIGMS NIH HHS SC1 GM139727NIMHD NIH HHS U54 MD019970
6 · The paper itself

Abstract

Cervical cancer is the fourth most common cancer among women worldwide and remains a significant cause of cancer-related mortality. Alcohol consumption is linked to an increased risk of several cancers and is a controversial risk factor for developing cervical cancer. This review updates existing information on the correlation between alcohol consumption and the risk of developing cervical cancer. Several comprehensive studies from different geographical regions have shown that moderate and heavy drinking is positively correlated with the development of cervical cancer. There is a synergistic relationship between human papillomavirus (HPV) viral load and alcohol use among drinkers with a high HPV viral load. Excessive alcohol consumption and exposure to second-hand smoke may elevate the risk of persistent HPV infection. Furthermore, high-risk behaviors associated with Human immunodeficiency virus (HIV)/HPV co-infection are more common among binge drinkers. However, several observations failed to establish a relationship between these factors. Despite some inconsistency in the literature, evidence suggests a modest association between alcohol consumption and increased risk of persistent HPV infection, causing cervical cancer.

Indexed as

Alcohol DrinkingCarcinogenesisUterine Cervical NeoplasmsFemaleHumansPapillomaviridaePapillomavirus InfectionsRisk Factorsalcohol consumptioncervical cancerHIV/HPV co-infectionimmune responserisk factorssmoking

Identifiers

PMID41148854
PMCPMC12564792

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.