Evidence map›Paper›PMID 41148825›Full record

ArticleCells2025

Estrogen Receptor Regulates Male Satellite Cells in a Female, but Not Male, Environment.

Ahmed S Shams, Brian P Sullivan, Erik A Toso, Dawn A Lowe, Michael Kyba

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Elevated mitochondrial CaStem cell reports · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ahmed S ShamsLillehei Heart Institute and Department of Pediatrics, Medical School, University of Minnesota, Minneapolis, MN 55455, USA.ORCID 0000-0003-1504-4367
Brian P SullivanDivision of Physical Therapy and Rehabilitation Science, Department of Family Medicine and Community Health, Medical School, University of Minnesota, Minneapolis, MN 55455, USA.
Erik A TosoLillehei Heart Institute and Department of Pediatrics, Medical School, University of Minnesota, Minneapolis, MN 55455, USA.ORCID 0000-0001-6527-3921
Dawn A LoweDivision of Physical Therapy and Rehabilitation Science, Department of Family Medicine and Community Health, Medical School, University of Minnesota, Minneapolis, MN 55455, USA.
Michael KybaLillehei Heart Institute and Department of Pediatrics, Medical School, University of Minnesota, Minneapolis, MN 55455, USA.ORCID 0000-0002-5579-7534

Funding

TRAINING PROGRAM IN MUSCLE RESEARCHT32AR007612 · NIAMS · UNIVERSITY OF MINNESOTA TWIN CITIES · PI JAMES M ERVASTI, DAWN A LOWE · 2001 to 2026
$11.3M
Dissecting Effects of Estrogen Deficiency on Satellite Cells and Muscle Regeneration in Females and MalesR01AG062899 · NIA · UNIVERSITY OF MINNESOTA · PI KYBA, MICHAEL, LOWE, DAWN A · 2019 to 2023
$2.5M
NIAMS NIH HHS T32 AR007612NIA NIH HHS R01 AG062899NIH HHS 1R01AG062899-01
6 · The paper itself

Abstract

Skeletal muscle homeostasis is dependent on the satellite cell pool, which is regulated by numerous signaling pathways. Estradiol (E2) function via estrogen receptor alpha (ERα,

Indexed as

Estrogen Receptor alphaSatellite Cells, Skeletal MuscleSex CharacteristicsAnimalsCell DifferentiationCell ProliferationEstradiolFemaleMaleMiceMice, Inbred C57BLSignal TransductionEstradiolEstrogen Receptor alpha17β-estradiolestrogenestrogen receptorregenerationsatellite cellssex hormonesskeletal muscletransplantation

Identifiers

PMID41148825
PMCPMC12564696

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.