Evidence map›Paper›PMID 41148812›Full record

ArticleCells2025

Jun-Yi Zhu, Hannah Seah, Hangnoh Lee, Hanhan Liu, Zhe Han

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jun-Yi ZhuCenter for Precision Disease Modeling, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA.ORCID 0000-0002-4517-101X
Hannah SeahCenter for Precision Disease Modeling, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
Hangnoh LeeCenter for Precision Disease Modeling, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
Hanhan LiuCenter for Precision Disease Modeling, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
Zhe HanCenter for Precision Disease Modeling, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA.ORCID 0000-0002-5177-7798

Funding

Screen and functional validation of Pediatric Cardiomyopathy genetic variants in DrosophilaR01HD111480 · NICHD · UNIVERSITY OF MARYLAND BALTIMORE · PI ZHE HAN · 2023 to 2026
$2.6M
INCLUDE19-Ancestral roles of histone-modifying genes in heart development and diseaseR01HL134940 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI HAN, ZHE · 2017 to 2020
$2.4M
Functional characterization of genes and genetic variants associated with hypoplastic heart syndrome in DrosophilaR01HL180768 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI ZHE HAN · 2025 to 2026
$1.5M
NHLBI NIH HHS R01 HL134940NHLBI NIH HHS R01 HL180768NICHD NIH HHS R01 HD111480NIH HHS 1R01HD111480-01NIH HHS 1R01HL134940-04NIH HHS 1R01HL180768-01
6 · The paper itself

Abstract

N-terminal acetylation, catalyzed by N-terminal acetyltransferase (NAT) complexes, is one of the most prevalent protein modifications in eukaryotic cells, yet its role in heart development remains poorly understood. Here, we use

Indexed as

Drosophila melanogasterDrosophila ProteinsHeartHeart Defects, CongenitalAnimalsDisease Models, AnimalHumansDrosophila Proteinscongenital heart diseaseDrosophilaheart developmentNAA16 variant validationN-terminal acetyltransferase

Identifiers

PMID41148812
PMCPMC12564477

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.