Evidence map›Paper›PMID 41148795›Full record

ArticleCells2025

TRIC-A Facilitates Sarcoplasmic Reticulum-Mitochondrial Ca

Ang Li, Xinyu Zhou, Ki Ho Park, Jianxun Yi, Xuejun Li, Jae-Kyun Ko, Yuchen Chen, Miyuki Nishi, Daiju Yamazaki, Hiroshi Takeshima and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ang LiDepartment of Kinesiology, College of Nursing and Health Innovation, University of Texas at Arlington, Arlington, TX 76010, USA.ORCID 0000-0002-8784-4702
Xinyu ZhouDepartment of Surgery, Division of Surgical Sciences, University of Virginia, Charlottesville, VA 22903, USA.
Ki Ho ParkDepartment of Surgery, Division of Surgical Sciences, University of Virginia, Charlottesville, VA 22903, USA.ORCID 0000-0002-6193-9826
Jianxun YiDepartment of Kinesiology, College of Nursing and Health Innovation, University of Texas at Arlington, Arlington, TX 76010, USA.
Xuejun LiDepartment of Kinesiology, College of Nursing and Health Innovation, University of Texas at Arlington, Arlington, TX 76010, USA.
Jae-Kyun KoDepartment of Surgery, Division of Surgical Sciences, University of Virginia, Charlottesville, VA 22903, USA.ORCID 0000-0001-9174-5806
Yuchen ChenDepartment of Surgery, Division of Surgical Sciences, University of Virginia, Charlottesville, VA 22903, USA.
Miyuki NishiDepartment of Pharmacology, Kyoto University, Kyoto 606-8501, Japan.
Daiju YamazakiDivision of Pharmacology, National Institute of Health Sciences, Tokyo 158-8501, Japan.
Hiroshi TakeshimaDepartment of Pharmacology, Kyoto University, Kyoto 606-8501, Japan.
Jingsong ZhouDepartment of Kinesiology, College of Nursing and Health Innovation, University of Texas at Arlington, Arlington, TX 76010, USA.
Jianjie MaDepartment of Surgery, Division of Surgical Sciences, University of Virginia, Charlottesville, VA 22903, USA.

Funding

Mitigating neuroinflammation and enhancing neuronal integrity in Alzheimer's diseaseR01AG072430 · NIA · UNIVERSITY OF VIRGINIA · PI Jianjie Ma · 2022 to 2026
$3.4M
MG53 function in muscle agingR01AG071676 · NIA · UNIVERSITY OF VIRGINIA · PI Jianjie Ma, Ki Ho Park · 2022 to 2026
$3.1M
Preserving Mitochondrial Function for Alleviating ALS ProgressionR01NS105621 · NINDS · UNIVERSITY OF TEXAS ARLINGTON · PI BROTTO, MARCO, ZHOU, JINGSONG · 2019 to 2023
$2.9M
Protein therapy to treat virus induced cardiopulmonary injuryR01HL157215 · NHLBI · UNIVERSITY OF VIRGINIA · PI CAI, CHUANXI, MA, JIANJIE · 2022 to 2025
$2.7M
Ca signaling cross-talk from SR to mitochondria in heart muscleR01HL138570 · NHLBI · OHIO STATE UNIVERSITY · PI LIN, PEI-HUI, ZHOU, JINGSONG · 2018 to 2021
$2.6M
Multifaceted role of MG53 in alleviating neuromuscular function decline in ALSR01NS129219 · NINDS · UNIVERSITY OF TEXAS ARLINGTON · PI Jianjie Ma, Lyle Wilfred Ostrow · 2023 to 2026
$2.5M
Targeting the multicellular process of corneal regeneration and vascularization to enhance outcome of cornea transplantationR01EY036243 · NEI · UNIVERSITY OF VIRGINIA · PI Heather Chandler, Jianjie Ma · 2024 to 2026
$2.1M
NEI NIH HHS R01 EY036243NHLBI NIH HHS R01 HL138570NHLBI NIH HHS R01 HL157215NIA NIH HHS R01 AG071676NIA NIH HHS R01 AG072430NIH HHS 5R01AG071676-04NIH HHS 5R01AG072430-04NIH HHS 5R01EY036243-02NIH HHS 5R01HL138570-02NIH HHS 5R01HL157215-05NIH HHS 5R01NS105621-05NIH HHS 5R01NS129219-04NINDS NIH HHS R01 NS105621NINDS NIH HHS R01 NS129219
6 · The paper itself

Abstract

TRIC-A is an intracellular cation channel enriched in excitable tissues that is recently identified as a key modulator of sarcoplasmic reticulum (SR) Ca

Indexed as

CalciumCalcium SignalingMitochondriaMyocytes, CardiacSarcoplasmic ReticulumAnimalsCardiomegalyHEK293 CellsHumansMaleMiceMice, Inbred C57BLMice, KnockoutOxidative StressRyanodine Receptor Calcium Release ChannelSodium-Calcium ExchangerCalciumRyanodine Receptor Calcium Release ChannelSlc8b1protein, mouseSodium-Calcium ExchangerCa2+ biosensormitochondrial Ca2+ homeostasisreactive oxygen speciesSOICRTMEM38A

Identifiers

PMID41148795
PMCPMC12564512

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.