Evidence map›Paper›PMID 41148734›Full record

ArticleAntibiotics (Basel, Switzerland)2025

Evaluating the Link Between Postoperative Timing of Rifampicin Introduction and the Clinical and Microbiological Outcomes of Orthopedic Staphylococcal Implant Infections.

Valeria Dessert, Steven M Maurer, Marc S Maurer, David Albrecht, Mazda Farshad, İlker Uçkay

Abstract read
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In one paragraph

Article in Antibiotics (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Valeria DessertInternal Medicine, Balgrist University Hospital, University of Zurich, 8008 Zurich, Switzerland.
Steven M MaurerDepartment of Orthopedic Surgery, Balgrist University Hospital, University of Zurich, 8008 Zurich, Switzerland.ORCID 0000-0003-4346-0528
Marc S MaurerDepartment of Orthopedic Surgery, Balgrist University Hospital, University of Zurich, 8008 Zurich, Switzerland.
David AlbrechtDepartment of Orthopedic Surgery, Balgrist University Hospital, University of Zurich, 8008 Zurich, Switzerland.ORCID 0009-0007-6115-0159
Mazda FarshadDepartment of Orthopedic Surgery, Balgrist University Hospital, University of Zurich, 8008 Zurich, Switzerland.
İlker UçkayInfectiology, Unit for Clinical and Applied Research, Balgrist University Hospital, University of Zurich, 8008 Zurich, Switzerland.ORCID 0000-0002-5552-0973

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesIn staphylococcal implant infections, there is often discussion about the optimal postoperative timing of the introduction of rifampicin in the postoperative period with open wounds.

methodsWe reviewed all adult patients with residual staphylococcal implant infections between January 2014 and May 2024. We analyzed the delay to rifampicin use in relation to therapeutic failures, infection recurrences, and development of ultimate rifampicin resistance.

resultsAmong 103 independent infection episodes, 47 (46%) contained the pathogen

conclusionsIn our retrospective cohort of staphylococcal orthopedic implant infections, the timing of rifampicin introduction failed to alter clinical and microbiological outcomes.

Indexed as

clinical outcomesdelay of introductionimplant infectionsorthopedic surgeryrifampicinrifampicin resistance

Identifiers

PMID41148734
PMCPMC12561295

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