Evidence map›Paper›PMID 41148699›Full record

ArticleAntibiotics (Basel, Switzerland)2025

Imipenem/Relebactam Plus Aztreonam: First Reported Use in MDR

Luca Pipitò, Raffaella Rubino, Rita Immordino, Eleonora Bono, Teresa Fasciana, Celestino Bonura, Giovanni Maurizio Giammanco, Vincenzo Argano, Antonio Cascio

Abstract readCase Reports
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. In vitro activity of β-lactamase inhibitors avibactam, relebactam and vaborbactam in combination with aztreonam against metallo-β-lactamase producing Escherichia coli clinical isolates.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Luca PipitòDepartment of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties "G D'Alessandro", University of Palermo, 90133 Palermo, Italy.ORCID 0000-0002-1871-4285
Raffaella RubinoInfectious and Tropical Disease Unit and Sicilian Regional Reference Center for the Fight Against AIDS, AOU Policlinico "P. Giaccone", 90133 Palermo, Italy.
Rita ImmordinoMicrobiology and Virology Unit, AOU Policlinico "P. Giaccone", 90133 Palermo, Italy.
Eleonora BonoDepartment of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties "G D'Alessandro", University of Palermo, 90133 Palermo, Italy.
Teresa FascianaDepartment of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties "G D'Alessandro", University of Palermo, 90133 Palermo, Italy.
Celestino BonuraDepartment of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties "G D'Alessandro", University of Palermo, 90133 Palermo, Italy.ORCID 0000-0002-6250-9203
Giovanni Maurizio GiammancoDepartment of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties "G D'Alessandro", University of Palermo, 90133 Palermo, Italy.ORCID 0000-0002-7874-6289
Vincenzo ArganoUnit of Cardiac Surgery, University of Palermo, 90127 Palermo, Italy.
Antonio CascioDepartment of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties "G D'Alessandro", University of Palermo, 90133 Palermo, Italy.ORCID 0000-0002-1992-1796

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCarbapenem-resistant CASE DESCRIPTION: We describe a case of a 51-year-old male with a post-sternotomy surgical site infection and concurrent bacteremia caused by a CRKP. Sternal swab and mediastinal liquid culture results highlighted CRKP harboring

Indexed as

aztreonambacteremiacarbapenem-resistant Klebsiella pneumoniaeceftazidime-avibactam resistanceimipenem/cilastatin/relebactamKPC (Klebsiella pneumoniae carbapenemase)metallo-β-lactamases

Identifiers

PMID41148699
PMCPMC12561063

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.