Evidence map›Paper›PMID 41148698›Full record

ArticleAntibiotics (Basel, Switzerland)2025

In Silico Identification and Molecular Characterization of

Amanda Appel, Lily Velazco, Adit B Alreja, Kara LeClair, Aryaan P Duggal, Isha Vashee, Aji Mary Taal, Norberto Gonzalez-Juarbe, Derrick E Fouts

Abstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Bacteriocins fromFrontiers in microbiology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Amanda AppelInfectious Diseases, The J. Craig Venter Institute, Rockville, MD 20850, USA.ORCID 0009-0007-6187-4384
Lily VelazcoHuman Genomic Medicine, The J. Craig Venter Institute, Rockville, MD 20850, USA.
Adit B AlrejaCell Biology & Molecular Genetics Department, University of Maryland, College Park, MD 20742, USA.ORCID 0000-0003-3607-8005
Kara LeClairHuman Genomic Medicine, The J. Craig Venter Institute, Rockville, MD 20850, USA.
Aryaan P DuggalCell Biology & Molecular Genetics Department, University of Maryland, College Park, MD 20742, USA.ORCID 0000-0003-4095-2818
Isha VasheeCell Biology & Molecular Genetics Department, University of Maryland, College Park, MD 20742, USA.ORCID 0009-0003-5195-8198
Aji Mary TaalInfectious Diseases, The J. Craig Venter Institute, Rockville, MD 20850, USA.
Norberto Gonzalez-JuarbeInfectious Diseases, The J. Craig Venter Institute, Rockville, MD 20850, USA.ORCID 0000-0003-2481-698X
Derrick E FoutsInfectious Diseases, The J. Craig Venter Institute, Rockville, MD 20850, USA.ORCID 0000-0003-4323-7668

Funding

CDC HHS U54CK000603
6 · The paper itself

Abstract

BACKGROUND/

objectivesBiofilm formation by

methodsThirteen LAB isolates from the Human Microbiome Project were screened for anti-biofilm activity against

resultsConditioned media from five LAB species (

conclusionsOur study provides a comprehensive platform for the discovery and characterization of AMPs and supports using commensal bacteria to reduce, prevent, and decolonize biofilms from pathogenic bacteria in community and nosocomial settings.

Indexed as

Acinetobacter baumanniiantibiotic synergyantimicrobial peptidesbiofilm disruptionbioinformatic discoveryclass IIb bacteriocinESKAPElactic acid bacteria

Identifiers

PMID41148698
PMCPMC12561633

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.